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A 44-year-old member asked:

What does neonatal alloimune thrombocytopenia mean?

1 doctor answer3 doctors weighed in
Dr. Tanya Russo
Pediatrics 25 years experience
NAT: Neonatal (fetus or newborn under 1 month) alloimmune (immune response to foreign antigen) thrombocytopenia (low platelet count). NAT occurs when substances from mother's body pass into the baby's system, causing destruction of platelet cells.

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A 34-year-old member asked:

Neonatal alloimune thrombocytopenia treatment?

1 doctor answer3 doctors weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Platelet transfusion: If the fetus has an antigen on platelets that the mother lacks, she may make antibodies that destroy the fetal platelets. Infusing platelets that lack the antigen is the treatment. Platelets can be infused into the fetus in utero, if needed, .
A 42-year-old member asked:

Neonatal alloimune thrombocytopenia, what is this?

1 doctor answer2 doctors weighed in
Dr. Jay Park
Dr. Jay Parkanswered
Pediatrics 50 years experience
Low platelets count: Neonatal alloimmune thrombocytopenia occurs when fetal platelets contain an antigen inherited from the father that the mother lacks. The mother forms antiplatelet antibodies against the this antigen; these cross the placenta and destroy fetal platelets, resulting in fetal and neonatal thrombocytopenia. Minority of affected newborns (about 20%) experiences severe bleeding including intracranial bl

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Last updated Nov 4, 2014
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