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A 29-year-old female asked:

My mom had invasive lobular breast cancer. is that more hereditary than invasive ductal?

2 doctor answers3 doctors weighed in
Dr. David Satloff
Pain Management 40 years experience
Controversial opinio: Dr Rau of the Paracelsus Institute has found that most cases of invasive breast cancer are due to poor root canal therapy outcomes draining from the mandible on the same side. The issue with unresolved mandibular infection is more important than genetic factors in predicting such cancer development. I find that the issue is more related to jaw infection than RCT involvement.
Dr. Carlos Encarnacion
Medical Oncology 35 years experience
Probably no, but...: Most of the statistics I have seen show similar rates of lobular cancer in carriers of BRCA 1/2 mutations (which is the most common recognizable inherited breast cancer trait) compared to non-carriers. Exception: carriers of CDH1 mutations (hereditary diffuse gastric cancer syndrome) have high risk for aggressive stomach cancer and lobular breast cancer.

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NJ
A 29-year-old female asked:

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

1 doctor answer2 doctors weighed in
Dr. Hernani Cualing
Pathology 30 years experience
No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p

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Last updated Feb 16, 2015

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