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A 29-year-old female asked:

Can folic acid prevent lamotrigine causing all birth defects during pregnancy?

1 doctor answer4 doctors weighed in
Dr. Jan Lei Iwata
Dr. Jan Lei Iwataanswered
Ophthalmology 27 years experience
Any drug causing: birth defects is separate from taking a supplement to support neurological development in pregnancy. Most supplements don't and aren't designed to prevent against birth defects. If you are concerned about this, discuss it with your OB/GYN doctor, and get a full evaluation of what you're taking, and what your concerns are. So, you can have piece of mind. Taking too much folic acid is not wise too.
Dr. Rhonda Simons
Family Medicine 16 years experience
Also 84% of the US population is not able to process synthetic folic acid--we must take the "end product" instead: L-methylfolate. I prefer a compound from Bellevue pharmacy that is covered by most insurance, while the rest are expensive and rejected by insurance companies as "medical foods". To a person with a MTHFR defect (677 or 1298), regular folic acid is close to "poison".
Aug 6, 2014

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A 29-year-old female asked:

Will folic acid prevent Lamotrigine causing birth defects during pregnancy?

1 doctor answer3 doctors weighed in
Dr. Heidi Fowler
Psychiatry 26 years experience
Lamictal is FDA: Pregnancy Category C. It would not be safe to assume that use of Folic Acid would be protective for potential side effects related to lamictal.
Dr. Rhonda Simons
Family Medicine 16 years experience
Test for MTHFR 677 & 1298, if positive, you need 15mg of L-methylfolate daily when taking lamicta. If negative (only 16% of the US population are), then regular folic acid is okay. Most of us have a defect in our folate metabolism that requires the special stuff-my fav is a compounded one from Bellevue pharmacy called "S8", covered by insurance!!!
Aug 6, 2014
Last updated Sep 28, 2016


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