A 40-year-old member asked:
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can you tell me in sepsis, how much bacteria needs to be in a person's blood before he start showing signs and symptoms?

1 doctor answer
Dr. Gurmukh Singh
48 years experience Pathology
Depends: We all get bacteria in our blood periodically, like after brushing teeth. Sepsis results when bacterial grow unchecked, produce chemical mediators, and the body may over-react. Bacteria do not need to be in blood to produce a picture of sepsis, e.g., massive activation of T-cells can cause picture of sepsis by exposure to superantigens.
Answered on May 24, 2015

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