A 39-year-old member asked:
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Can you tell me how is the gene for alpha thalassemia an adaptive trait?

1 doctor answer
Dr. Louis Cooper
47 years experience in Pediatrics
Adaptive?: Not certain what you mean. Alpha Thal trait is a genetic--hereditary finding, which was shared with you by either your Mom or Dad. It is not adaptive as sickle cell trai/disease to help prevent malaria, to my knowledge.
Answered on Aug 17, 2014

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A 61-year-old member asked:
Dr. Robert Kwok
32 years experience in Pediatrics
No: Alpha thalassemia trait only causes mild anemia, and the person usually has no symptoms. Gene therapy is not available and would not be needed.
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A 59-year-old member asked:
Dr. Robert Kwok
32 years experience in Pediatrics
Not quite: Normal people have 4 Alpha globulin genes. Mutations in 1, 2, 3, or all 4 of the genes cause the 4 levels of Alpha thalassemia. One mutation = silent ... Read More
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A 45-year-old member asked:
Dr. Robert Kwok
32 years experience in Pediatrics
Yes, but unlikely: A person with Alpha thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more d ... Read More
A 41-year-old member asked:
Dr. Robert Kwok
32 years experience in Pediatrics
Maybe: A person with Alpha thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more d ... Read More

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