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A 33-year-old member asked:

can you tell me how is the gene for alpha thalassemia an adaptive trait?

1 doctor answer1 doctor weighed in
Dr. William Lages
Rheumatology 68 years experience
May be protective: Alpha thalassemia is found worldwide in the same geographic location as malaria. It is postulated that it protects in making the malaria less severe, but no rigorous studies have been done to prove this true or how it it molecularly protective.

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A 41-year-old member asked:

Which genetic tests can I take in the first trimester of pregnancy?

4 doctor answers6 doctors weighed in
Dr. Stephen Scarantino
Obstetrics and Gynecology 26 years experience
There are many: There are many screening tests that a patient may undertake to screen for genetic problems. What needs to be done is a proper family/genetic history and have genetic testing performed based upon that history. Nevertheless, general screeening for genetic problems will be offered by your obstetrician at different times during your pregnancy (ex.: down's syndrome testing).
A 24-year-old member asked:

If I have the single gene mutation (heterozygote) and am a "silent carrier" for hemochromatosis, will I become iron overloaded?

2 doctor answers6 doctors weighed in
Dr. Gregg Albers
Addiction Medicine 41 years experience
Hemachromatosis: The single gene carrier will likely not develop any symptoms or problems from increased iron absorption. You will still need to have regular blood work to check for increased iron, and not use any supplements with iron. If you have two genes, your chance is good that you will have high levels of iron, and possibly get damage from the extra iron. Timing is unknown, too many variables.
A 21-year-old member asked:

Is cord blood or bone marrow treatment best for thalassemia?

2 doctor answers4 doctors weighed in
Dr. Robert Kwok
Pediatrics 33 years experience
Maybe cord blood: Research is ongoing, but the hope is that stem cell transplantation from umbilical cord blood will be better tolerated (less rejection from the thalassemia patient) than donor bone marrow stem cell transplantation.
A 21-year-old member asked:

Is cerebral palsy a disease or a genetic disorder?

2 doctor answers3 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
It is an injury: CP results from an injury to the developing nervous system of fetus, newborn or todler caused by various events.Brain hemorrage, a cut off of oxygen, or occasionally tissue damage from a viral infection can produce the pattern. Each child is an individual event and > half of mild cases have no apparent cause.
A 33-year-old member asked:

Can surgery correct a blind eye due to a genetic problem?

1 doctor answer1 doctor weighed in
Dr. Yale Kanter
Ophthalmology 61 years experience
Genetic blindness: It depends on what the type of blindness is. If it affects the retina and optic nerve there is no corrective surgery for this. If it is due to a deep amblyopia there is no corrective surgery.

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Last updated Aug 17, 2014
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