A 32-year-old female asked:
Disclaimer

would myeloma-related proteins or an m spike show up in routine blood tests - or specialized tests only? what about protein in routine urine test?

1 doctor answer
Dr. Carlos Encarnacion
35 years experience Medical Oncology
Yes/no/maybe: A routine chemistry may show an elevation in the total protein or globulin levels plus or minus high calcium or kidney dysfunction but the ultimate diagnosis is made with an SPEP + IFE. Urine electrophoresis may also show the protein if it's small enough to filter through. That is not always the case, though.
Answered on May 16, 2014
1
1 thank

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
24/7 visits
$15 per month

Related questions:

A 26-year-old male asked:
Dr. Gurmukh Singh
49 years experience Pathology
Not necessarily: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ... Read More
A 50-year-old female asked:
Dr. Donald Colantino
61 years experience Internal Medicine
Cancer: Rarely multiple myeloma can be present with normal serum electrophoresis but immunofixation may show it. Your free light chain assay showed what you s ... Read More
1
1 thank
A 31-year-old male asked:
Dr. Gurmukh Singh
49 years experience Pathology
False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich i ... Read More
1
1 thank
A 26-year-old male asked:
Dr. Donald Colantino
61 years experience Internal Medicine
Light chains: Measurement and identification of free light chains in a blood test will demonstrate the presence of abnormal amounts of immunoglobulins and thus m ... Read More

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
24/7 visits
$15 per month