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A member asked:

i've been taking advicor for five years and now my doctor is switching me to zocor (simvastatin). how long does the niacin stay in your body.. flushing?

2 doctor answers7 doctors weighed in
Dr. Bennett Werner
Cardiology 44 years experience
Good question: I researched your question: the half life of extended release Niacin in Advicor (lovastatin and niacin) is very variable, & depends on gender, dose, & individual characteristics. It peaks 5 hours after a single dose. Following years of treatment, it's probably safe to assume that it will take days (3-5) to wear off completely. Possibly longer depending on dose.
Dr. Gloria Fong
Family Medicine 40 years experience
Less than a week: I usually taper meds down and then switch to the newer medication just to make sure there is not an interaction with muscle aches since the two medications together can cause this problem.

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Last updated Apr 11, 2018
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