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A 48-year-old male asked:

I switch from cymbalta (duloxetine) 90mg to zoloft 50mg by tapering cymbalta (duloxetine) but after 10 dayes i finish my last 30 mg cymbalta (duloxetine) but i can't sleep even with trazadon?

1 doctor answer3 doctors weighed in
Dr. Robert Grieco
Family Medicine 37 years experience
May take longer. : Zoloft and Cymbalta (duloxetine) are actually very different from each other. Cymbalta (duloxetine) is very potent and works on two different receptors (serotonin ; norepinephrine ) and many people take longer to get off of it. Zoloft works mostly on one (receptor) and 50 mg is a low dose. Talk to your doctor about this.

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Last updated May 20, 2018

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