A male asked:
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zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? thoughts?

3 doctor answers
Dr. Liawaty Ho
23 years experience Hematology and Oncology
Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you.
Answered on Nov 27, 2017
Dr. Sewa Legha
50 years experience Medical Oncology
Both valuable: Both of these drugs have shown remarkable benefit. We have more experience with zytiga(abiraterone), so i prefer this drug but you will likely benefit from both as they have different mechanism of action.
Answered on Nov 27, 2017
Dr. John Nesbitt
A Verified Doctor answered
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Consider Provenge (sipuleucel-t): Provenge (Sipuleucel-T) should be considered in chemo naive patients, probably before Zytiga (abiraterone acetate) or Xtandi. It costs about $100,000 at present. If you decide to bypass the immunotherapy, just remember to give prednisone with the Zytiga (abiraterone acetate). Both can deliver several additional months of survival.
Answered on Nov 27, 2017
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1 comment
Dr. Michael Thompson
20 years experience Hematology and Oncology
If asymptomatic. Provenge approved before Zytiga and Xtandi (etc) out so may not have been approved in current environment.
Nov 18, 2015

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