A 36-year-old member asked:
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is only decrease in food intake responsible for the weight loss assicated with cancer cachexia?

2 doctor answers
Dr. Joseph Woods
27 years experience Pathology
No.: The mechanism is poorly understood, but even nutrition cannot reverse this condition. In cancer patients, it is thought to involve inflammatory cytokines like tumor necrosis factor-alpha (tnf-α), also called cachexin for this reason. Interferon gamma (ifnγ), and interleukin 6 (il-6), as well as the tumor-secreted proteolysis inducing factor (pif) are other cytokines involved.
Answered on Dec 22, 2016
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Dr. Melissa Young
8 years experience Internal Medicine
No: There is also an increase in calorie expenditure.
Answered on Jul 5, 2012

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