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A 73-year-old male asked:

I have been told that vitamin k may be administered subcutaneously but should not be administered intravenously in adults. if this is correct then why is this so?

2 doctor answers4 doctors weighed in
Dr. Gregory Lewis
Urology 44 years experience
See answer: In order of highest to lowest preference, vit k can be given orally (po), subcutaneously (sq), intramuscular (im), or intravenous (iv). The injectable form of vitamin k can rarely cause severe (sometimes fatal) allergic reactions when given by im or iv. Therefore, vitamin k should only be given im or slowly IV if rapid or immediate correction of over-anticoagulation is required.
Dr. Robert Pearson-Martinez
Pediatric Cardiology 20 years experience
Risk of anaphylaxis: If given iv, there is a risk of an anaphylactic reaction (life-threatening allergic reaction). Vitamin k generally is given by an intramuscular or im injection. If given iv, it should be infused very slowly, while monitoring closely for any adverse reaction.

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