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A 42-year-old member asked:

please explain why is narcan (naloxone) ( narcotic antagonist) given to cancel out stadol in l&d since stadol is not a narcotic ?

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Dr. Alan Wartenberg
A Verified Doctor answered
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Stadol is a narcotic: Narcotic is actually a legal, not a medical term, but stadol (butorphanol) is a synthetic opioid, which acts on the kappa receptors, which are opioid pain receptors, but blocks the mu receptor (another pain receptor) - it is called a mixed agonist/antagonist. The effects of the rug usually don't need to be reversed, but Naloxone (narcan) will block the kappa effects of stadol.

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Last updated Jun 30, 2014
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