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A 39-year-old member asked:

Is it true that adrenal insufficiency is hereditary?

1 doctor answer2 doctors weighed in
Dr. Thomas Knecht
A Verified Doctoranswered
A US doctor answeredLearn more
No: Hi. No, not as in a single gene defect. Adrenal enzyme deficiencies (one gene, 2 copies for each enzyme - 1 from mom & 1 from dad) are hereditary. Adrenal insufficiency is usually autoimmune, infectious, malignant, or hemorrhagic; not single gene defects.

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A 47-year-old member asked:

Is adrenal insufficiency hereditary?

2 doctor answers6 doctors weighed in
Dr. Susan Wingo
Endocrinology 33 years experience
It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families.
A 32-year-old member asked:

Is it true that addisons disease and adrenal insufficiency are the same?

2 doctor answers3 doctors weighed in
Dr. Mazen Kherallah
Infectious Disease 34 years experience
Addison: Addison disease is the decreased function of the adrenal gland with decreased level of aldosterone.

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Last updated Jul 3, 2014

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