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What genes play an important role in cerebrovascular disease?

2 doctor answers2 doctors weighed in
Dr. Michael Depietro
Pulmonary Critical Care 35 years experience
Many: Since there are many types of stroke, this is a very complicated question. Most strokes are related to atherosclerosis ( fat deposit in the arteries). So the genes involved ( there are many) in lipid (fat) metabolism and blood pressure regulation are important. One important set of genes seems to be located on chromosome number 9. In any case this is an active area of medical research.
Dr. Edward Smith
Neurosurgery 54 years experience
Many or none: Although many genes have been implicated in causing stroke syndromes, only a relatively few have been shown to have a definite correlation: examples include leiden factor v deficiency & cerebral amyloid angiopathy. There are others. However the majority of stroke syndromes seem to involve genes which are contributory but insufficient in themselves to cause stroke.

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Last updated Sep 30, 2012

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