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alpha thalassemia

A 54-year-old member asked:
Dr. Joseph Torkildson
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Conventional: As scientists investigated hemoglobin, the complicated compound in red blood cells that carries oxygen, they learned that it was made up of 5 parts; 4 ... Read More
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A 49-year-old member asked:
Dr. Robert Kwok
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Not quite: People normally have 4 Alpha globulin genes. A mutation in 1, 2, 3, or all 4 genes leads to the 4 levels of Alpha thalassemia. The genetics of the dis ... Read More
A 51-year-old member asked:
Dr. James Ball
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Hemoglobin problem: Alpha thal is caused by mutations that effect the production of a part of the hemoglobin molecule (Alpha chain). There are 4 genes involved in this p ... Read More
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A 34-year-old member asked:
Dr. Robert Kwok
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From Mom and/or Dad: Alpha thalassemia is caused by a mutation in one or more of the 4 genes that code for (holds the dna for) Alpha globulin, which is needed to make hemo ... Read More
A 42-year-old member asked:
Dr. Emily Lu
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Family history: Thalassemia is a genetic disease of the hemoglobin molecule and so only occurs through inheritance. A mutation in this gene is especially prevalent in ... Read More
A 41-year-old member asked:
Dr. Robert Kwok
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None to severe/fatal: Alpha thalassemia signs and symptoms: silent carriers have no signs/symptoms; Alpha trait has mild anemia; HGB h (moderate) may have weakness, pallor ... Read More
A 33-year-old member asked:
Dr. Robert Kwok
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None to severe/fatal: Alpha thalassemia signs and symptoms: silent carriers have no signs/symptoms (and live a normal life); Alpha trait has mild anemia (and generally live ... Read More
A 45-year-old member asked:
Dr. Hushang Haghighat
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Mild anemia: it could be mild hypochromic ,microcytic anemia.
A 52-year-old member asked:
Dr. James Ferguson
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Inherited defect: Our regular hemoglobin is composed of Alpha and beta chains that come together to form working hemaglobin. Alpha thalassemia trait occurs when a perso ... Read More
A 32-year-old female asked:
Dr. Sudhakar Rao
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Yes: Your height may be within the range but you are just short. Your internist must put you on the growth chart which tells you if you are at the lower en ... Read More

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