Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.
Nat. Chem. Biol., Apr;5(4):236-43 (2009)
Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.
Blood., Apr;111(8):4338-47 (2008)
Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia.
Genes Chromosomes Cancer., Nov;44(3):279-91 (2005)
Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.
Blood., May;111(9):4716-22 (2008)
Loss of heterozygosity in childhood de novo acute myelogenous leukemia.
Blood., Aug;98(4):1188-94 (2001)
Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia.
Blood., Jan;97(1):89-94 (2001)
Transgenic rescue of aganglionosis and piebaldism in lethal spotted mice.
Dev. Dyn., Jan;217(1):120-32 (2000)
Sympathoadrenal hyperplasia causes renal malformations in Ret(MEN2B)-transgenic mice.
Am. J. Pathol., Dec;155(6):2167-79 (1999)
Oncogenesis and altered differentiation induced by activated Ras in neuroblasts of transgenic mice.
Oncogene., Dec;15(23):2783-94 (1997)
Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice.
Oncogene., Jan;18(4):877-86 (1999)
The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands.
J. Biol. Chem., Apr;261(12):5553-61 (1986)
Rat cellular retinol-binding protein II: use of a cloned cDNA to define its primary structure, tissue-specific expression, and developmental regulation.
Proc. Natl. Acad. Sci. U.S.A., Aug;83(16):5779-83 (1986)
The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene.
J. Biol. Chem., Feb;262(6):2458-67 (1987)
The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships.
J. Biol. Chem., Nov;262(33):16060-71 (1987)
Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes.
Genes Dev., Oct;2(10):1318-32 (1988)
Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine.
Proc. Natl. Acad. Sci. U.S.A., Dec;85(24):9611-5 (1988)
A transgenic mouse model that is useful for analyzing cellular and geographic differentiation of the intestine during fetal development.
J. Biol. Chem., May;264(14):8419-29 (1989)
Schinzel-Giedion syndrome and congenital megacalyces.
Pediatr Radiol., 23(2):111-2 (1993)
Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C.
Genomics., Jan;25(1):309-11 (1995)
Intercellular signals downstream of endothelin receptor-B mediate colonization of the large intestine by enteric neuroblasts.
Development., Nov;121(11):3787-95 (1995)