Type I interferon: a new player in TNF signaling.
Curr. Dir. Autoimmun., 11:94-104 (2010)
Systemic lupus erythematosus monocytes are less responsive to interleukin-10 in the presence of immune complexes.
Arthritis Rheum., Jan;63(1):212-8 (2011)
Suppression of TNF-Î± and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
J. Immunol., Dec;185(11):7047-56 (2010)
IFN-Î³ abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling.
Proc. Natl. Acad. Sci. U.S.A., Nov;107(45):19438-43 (2010)
TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages.
Proc. Natl. Acad. Sci. U.S.A., Jan;108(4):1573-8 (2011)
Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.
Immunology., Apr;132(4):567-77 (2011)
How ITAMs inhibit signaling.
Sci Signal., 4(169):pe20 (2011)
Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors.
Arthritis Res. Ther., 13(4):234 (2011)
Inflammatory signaling in macrophages: transitions from acute to tolerant and alternative activation states.
Eur. J. Immunol., Sep;41(9):2477-81 (2011)
TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.
J. Exp. Med., Feb;209(2):319-34 (2012)
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.
J. Immunol., Apr;188(7):3447-57 (2012)
The IFN signature and STAT1 expression in RA synovial fluid macrophages are induced by TNFÎ± and counter-regulated by synovial fluid microenvironment.
Regulation of inflammatory responses in tumor necrosis factor - activated and rheumatoid arthritis synovial macrophages by Janus kinase inhibitors.
Arthritis Rheum., Aug (2012)
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression.
J. Immunol., Aug;183(4):2444-55 (2009)
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors.
J. Immunol., Dec;183(11):7223-33 (2009)
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.
Immunity., Oct;31(4):539-50 (2009)
Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis.
J. Orthop. Res., Jan;26(1):106-16 (2008)
Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages.
Proc. Natl. Acad. Sci. U.S.A., Feb;107(7):3012-7 (2010)
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.
Immunity., Apr;32(4):518-30 (2010)
Overview of the biology of type I interferons.
Arthritis Res. Ther., 12 Suppl 1:S1 (2010)