Lesioning noradrenergic neurons of the locus coeruleus in C57Bl/6 mice with unilateral 6-hydroxydopamine injection, to assess molecular, electrophysiological and biochemical changes in noradrenergic signaling.
Neuroscience., Aug;216:143-57 (2012)
Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease.
Brain Res., Feb;1373:240-52 (2011)
Prazosin treatment of trauma nightmares and sleep disturbance in soldiers deployed in Iraq.
J Trauma Stress., Oct;23(5):645-8 (2010)
Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptoms.
Neuroimage., Jan;54 Suppl 1:S76-82 (2011)
A comprehensive analysis of the effect of DSP4 on the locus coeruleus noradrenergic system in the rat.
Neuroscience., Mar;166(1):279-91 (2010)
Prazosin for the treatment of behavioral symptoms in patients with Alzheimer disease with agitation and aggression.
Am J Geriatr Psychiatry., Sep;17(9):744-51 (2009)
Preclinical evidence of Alzheimer changes: convergent cerebrospinal fluid biomarker and fluorodeoxyglucose positron emission tomography findings.
Arch. Neurol., May;66(5):632-7 (2009)
Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin.
J Trauma Stress., Aug;21(4):417-20 (2008)
Diagnosis and treatment of depression comorbid with neurologic disorders.
Am. J. Med., Nov;121(11 Suppl 2):S28-37 (2008)
Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study.
Biol. Psychiatry., Mar;63(6):629-32 (2008)
Characterization of verbal and spatial memory changes from moderate to supraphysiological increases in serum testosterone in healthy older men.
Psychoneuroendocrinology., Jan;32(1):72-9 (2007)
Changes in adrenoreceptors in the prefrontal cortex of subjects with dementia: evidence of compensatory changes.
Neuroscience., Apr;146(1):471-80 (2007)
Chronic daily ethanol and withdrawal: 6. Effects on rat sympathoadrenal activity during "abstinence".
Alcohol., Apr;38(3):173-7 (2006)
Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition.
Arch. Neurol., Jul;63(7):936-9 (2006)
Olanzapine-induced weight gain and increased visceral adiposity is blocked by melatonin replacement therapy in rats.
Neuropsychopharmacology., Feb;32(2):284-8 (2007)
Safety and acceptability of the research lumbar puncture.
Alzheimer Dis Assoc Disord., 19(4):220-5 (2005)
Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.
J. Neurosci., Jan;26(2):467-78 (2006)
Salivary cortisol and memory function in human aging.
Neurobiol. Aging., Nov;27(11):1705-14 (2006)
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.
Int Psychogeriatr., Jun;17(2):313-8 (2005)
Alpha1-adrenoreceptor in human hippocampus: binding and receptor subtype mRNA expression.
Brain Res. Mol. Brain Res., Oct;139(2):367-71 (2005)