Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer.
Cancer Res., Aug;70(16):6497-508 (2010)
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1.
J. Clin. Oncol., Mar;29(7):917-24 (2011)
Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.
Neoplasia., Feb;13(2):145-53 (2011)
Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.
J. Natl. Cancer Inst., Jun;103(12):962-78 (2011)
Gastrointestinal stromal tumor: psychosocial characteristics and considerations.
Support Care Cancer., Jun;20(6):1343-9 (2012)
Targeting the insulin growth factor receptor 1.
Hematol. Oncol. Clin. North Am., Jun;26(3):527-42, vii-viii (2012)
Hypocalcemia in a patient with osteosarcoma and 22q11.2 deletion syndrome.
J. Pediatr. Hematol. Oncol., Aug;30(8):612-7 (2008)
Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody.
Cancer Res., Oct;68(19):8039-48 (2008)
The role of IGF-1R in pediatric malignancies.
Oncologist., Jan;14(1):83-91 (2009)
Targeting IGF-1R in the treatment of sarcomas: past, present and future.
Bull Cancer., 96(7):E52-60 (2009)
Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.
J. Clin. Invest., Nov;119(11):3395-407 (2009)
The biology behind mTOR inhibition in sarcoma.
Oncologist., Aug;12(8):1007-18 (2007)
Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases.
Clin. Exp. Metastasis., 25(3):201-11 (2008)
Low Dose Histone Deacetylase Inhibitor, Depsipeptide (FR901228), Promotes Adenoviral Transduction in Human Rhabdomyosarcoma Cell Lines.
Sarcoma., 8(1):25-30 (2004)
A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.
Clin. Cancer Res., Aug;14(15):4850-8 (2008)
Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors.
Cancer Res., Feb;66(3):1818-23 (2006)
CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta.
Cancer Res., Apr;66(7):3869-75 (2006)
CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling.
Neoplasia., May;8(5):394-401 (2006)
The molecular biology of pulmonary metastasis.
Thorac Surg Clin., May;16(2):115-24 (2006)
Ezrin mediates growth and survival in Ewing's sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway.
Clin. Exp. Metastasis., 23(3-4):227-36 (2006)