T-helper type 2-driven inflammation defines major subphenotypes of asthma.
Am. J. Respir. Crit. Care Med., Sep;180(5):388-95 (2009)
Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.
Am. J. Respir. Crit. Care Med., Oct;180(7):603-10 (2009)
DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2.
J. Immunol., Jun;184(11):6522-8 (2010)
Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma.
Proc. Natl. Acad. Sci. U.S.A., Aug;107(32):14170-5 (2010)
Allergen challenge causes inflammation but not goblet cell degranulation in asthmatic subjects.
J. Allergy Clin. Immunol., Nov;108(5):784-90 (2001)
A prospective multicenter study of factors associated with hospital admission among adults with acute asthma.
Am. J. Med., Oct;113(5):371-8 (2002)
Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression.
Am. J. Respir. Crit. Care Med., May;169(9):1001-6 (2004)
Airway remodeling in asthma.
Semin Respir Crit Care Med., Aug;23(4):361-7 (2002)
A distinctive alveolar macrophage activation state induced by cigarette smoking.
Am. J. Respir. Crit. Care Med., Dec;172(11):1383-92 (2005)
Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction.
Chest., Oct;130(4):1102-8 (2006)
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.
Proc. Natl. Acad. Sci. U.S.A., Oct;104(40):15858-63 (2007)
Gene expression in asthmatic airway smooth muscle.
Proc Am Thorac Soc., Jan;5(1):113-8 (2008)
Prevalence and risk factors for depressive symptoms in persons with chronic obstructive pulmonary disease.
J Gen Intern Med., Nov;23(11):1757-62 (2008)
Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit.
J. Allergy Clin. Immunol., Nov;122(5):944-950.e3 (2008)
Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice.
COPD., Apr;6(2):86-94 (2009)
Asthma: prevalence, pathogenesis, and prospects for novel therapies.
JAMA., Jul;286(4):395-8 (2001)
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma.
J. Allergy Clin. Immunol., Nov;108(5):753-8 (2001)
Structural changes to airway smooth muscle in cystic fibrosis.
Thorax., Mar;60(3):226-8 (2005)
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease.
Am. J. Respir. Crit. Care Med., Mar;181(5):438-45 (2010)
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma.
J. Allergy Clin. Immunol., May;125(5):1046-1053.e8 (2010)