Initial treatment patterns over time for anaplastic oligodendroglial tumors.
Neuro-oncology., Jun;14(6):761-7 (2012)
Prospective, high-throughput molecular profiling of human gliomas.
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
J. Natl. Cancer Inst., Jan;104(1):42-55 (2012)
Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor.
J. Clin. Oncol., Jan;30(3):e30-3 (2012)
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.
Cancer Cell., Dec;20(6):810-7 (2011)
Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.
Neuro-oncology., Feb;14(2):132-44 (2012)
A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53.
J. Neuropathol. Exp. Neurol., Feb;70(2):110-5 (2011)
Polysomy for chromosomes 1 and 19 predicts earlier recurrence in anaplastic oligodendrogliomas with concurrent 1p/19q loss.
Clin. Cancer Res., Oct;15(20):6430-7 (2009)
Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome.
J. Neuropathol. Exp. Neurol., Oct;68(10):1155-65 (2009)
Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations.
Arch. Pathol. Lab. Med., Dec;133(12):1949-53 (2009)
Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression.
Cancer Res., Mar;70(6):2350-8 (2010)
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res., Mar;70(6):2158-64 (2010)
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.
Oncogene., Jun;29(22):3185-95 (2010)
Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine.
EMBO Mol Med., May;2(5):146-58 (2010)
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma.
J. Clin. Oncol., Jun;28(17):2817-23 (2010)
Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers.
Lancet Neurol., Jul;9(7):717-26 (2010)
Bone involvement predicts poor outcome in atypical meningioma.
J. Neurosurg., Sep;111(3):464-71 (2009)
What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator.
Cell Cycle., Sep;7(18):2833-9 (2008)
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
Nat. Biotechnol., Jan;27(1):77-83 (2009)
Expression of oligodendroglial and astrocytic lineage markers in diffuse gliomas: use of YKL-40, ApoE, ASCL1, and NKX2-2.
J. Neuropathol. Exp. Neurol., Dec;65(12):1149-56 (2006)
Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival.
J. Neuropathol. Exp. Neurol., Dec;65(12):1181-8 (2006)
Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma.
Genes Dev., Jan;21(1):98-111 (2007)
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Cancer Cell., Jan;11(1):83-95 (2007)
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
Neuron., Feb;53(4):503-17 (2007)
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
Clin. Cancer Res., Apr;13(7):2038-45 (2007)
Survey of treatment recommendations for anaplastic oligodendroglioma.
Neuro-oncology., Jul;9(3):314-8 (2007)
Tests of association under misclassification: application to histological sampling in oncology.
Stat Med., Nov;26(26):4808-16 (2007)
The 2007 WHO classification of tumours of the central nervous system.
Acta Neuropathol., Aug;114(2):97-109 (2007)
Molecular pathology of malignant gliomas.
Annu Rev Pathol., 1:97-117 (2006)
Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers.
J. Neuropathol. Exp. Neurol., Jan;67(1):1-15 (2008)
A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
J. Neurooncol., Sep;89(2):187-93 (2008)
Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness.
J. Neurosci., Jun;28(23):5870-8 (2008)
"MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management?
J Mol Diagn., Jul;10(4):308-10 (2008)
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma.
Proc. Natl. Acad. Sci. U.S.A., Aug;105(31):10703-8 (2008)
Tissue injury from tricyclic antidepressants used as local anesthetics.
Anesth. Analg., Dec;101(6):1838-43 (2005)
Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma.
Clin. Cancer Res., Dec;11(24 Pt 1):8600-5 (2005)
A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations.
Biostatistics., Jul;7(3):399-421 (2006)
Glioma test array for use with formalin-fixed, paraffin-embedded tissue: array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization.
J Mol Diagn., May;8(2):268-76 (2006)
Epidermal growth factor receptor mutation testing in the care of lung cancer patients.
Clin. Cancer Res., Jul;12(14 Pt 2):4403s-4408s (2006)
Downregulation of RUNX3 and TES by hypermethylation in glioblastoma.
Oncogene., Jan;26(4):583-93 (2007)
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.
Cancer Res., Dec;66(23):11502-13 (2006)
YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas.
Clin. Cancer Res., Mar;11(6):2258-64 (2005)
Statistical considerations for immunohistochemistry panel development after gene expression profiling of human cancers.
J Mol Diagn., May;7(2):276-82 (2005)
Genetic analyses for predictors of radiation response in glioblastoma.
Int. J. Radiat. Oncol. Biol. Phys., Nov;63(3):704-10 (2005)
Alterations in p53, p21, and MIB-1 labeling index in primary human astrocytomas following radiation therapy.
J. Neurooncol., Sep;74(2):151-4 (2005)
Histology-based expression profiling yields novel prognostic markers in human glioblastoma.
J. Neuropathol. Exp. Neurol., Nov;64(11):948-55 (2005)
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
Brain Pathol., Oct;14(4):372-7 (2004)
Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
Neuro-oncology., Jan;7(1):97-100 (2005)
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.
J. Neuropathol. Exp. Neurol., May;63(5):499-509 (2004)
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
N. Engl. J. Med., May;350(21):2129-39 (2004)
Pigmented central neurocytoma.
Acta Neuropathol., Jun;107(6):571-4 (2004)
The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.
Am. J. Pathol., Mar;164(3):1031-8 (2004)
An ultra-high speed whole slide image viewing system.
Stud Health Technol Inform., 179:239-49 (2012)
The Warrens and other pioneering clinician pathologists of the Massachusetts General Hospital during its early years: an appreciation on the 200th anniversary of the hospital founding.
Mod. Pathol., Oct;24(10):1285-94 (2011)
Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas.
Acta Neuropathol., Apr;121(4):529-43 (2011)
Application of signal processing techniques for estimating regions of copy number variations in human meningioma DNA.
Conf Proc IEEE Eng Med Biol Soc., 2009:6973-6 (2009)
In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation.
Am. J. Pathol., Nov;167(5):1379-87 (2005)
CD155/PVR plays a key role in cell motility during tumor cell invasion and migration.
BMC Cancer., Oct;4:73 (2004)