Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.
Circulation., Jul;126(1):76-82 (2012)
Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis.
J. Rheumatol., Mar;39(3):510-5 (2012)
Preferential transmission of genetic risk variants of candidate loci at 6p21 from asymptomatic grandparents to mothers of children with neonatal lupus.
Arthritis Rheum., Mar;64(3):931-9 (2012)
Use of pharmacogenetics, enzymatic phenotyping, and metabolite monitoring to guide treatment with azathioprine in patients with systemic lupus erythematosus.
J. Rheumatol., Jan;36(1):89-95 (2009)
Antibody reactivity to alpha-enolase in mothers of children with congenital heart block.
J. Rheumatol., Mar;36(3):565-9 (2009)
Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk.
J. Intern. Med., Jun;265(6):653-62 (2009)
Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal/fetal risk factors.
Arthritis Rheum., Oct;60(10):3091-7 (2009)
Updates on lupus and pregnancy.
Bull NYU Hosp Jt Dis., 67(3):271-5 (2009)
Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus.
Lupus., Mar;19(3):300-6 (2010)
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
J. Immunol., Feb;184(4):2148-55 (2010)
Cutaneous manifestations of neonatal lupus and risk of subsequent congenital heart block.
Arthritis Rheum., Apr;62(4):1153-7 (2010)
Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine.
Ann. Rheum. Dis., Oct;69(10):1827-30 (2010)
Role of the urokinase plasminogen activator receptor in mediating impaired efferocytosis of anti-SSA/Ro-bound apoptotic cardiocytes: Implications in the pathogenesis of congenital heart block.
Circ. Res., Aug;107(3):374-87 (2010)
Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.
Arthritis Rheum., Nov;62(11):3415-24 (2010)
Î²2-glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus.
J. Immunol., Jul;187(1):520-6 (2011)
A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block.
J. Biol. Chem., Sep;286(35):30444-54 (2011)
Maternal and fetal factors associated with mortality and morbidity in a multi-racial/ethnic registry of anti-SSA/Ro-associated cardiac neonatal lupus.
Circulation., Nov;124(18):1927-35 (2011)
Binding of anti-SSA antibodies to apoptotic fetal cardiocytes stimulates urokinase plasminogen activator (uPA)/uPA receptor-dependent activation of TGF-Î² and potentiates fibrosis.
J. Immunol., Nov;187(10):5392-401 (2011)
Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block.
J. Clin. Invest., Sep;116(9):2413-22 (2006)
The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial.
Arthritis Rheum., Nov;54(11):3623-32 (2006)
Neonatal lupus syndromes.
Rheum. Dis. Clin. North Am., May;33(2):267-85, vi (2007)
Epidemiology, etiology, detection, and treatment of autoantibody-associated congenital heart block in neonatal lupus.
Curr Rheumatol Rep., May;9(2):101-8 (2007)
Role of hypoxia and cAMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scarring in autoimmune-associated congenital heart block.
Arthritis Rheum., Dec;56(12):4120-31 (2007)
Disease progression in mothers of children enrolled in the Research Registry for Neonatal Lupus.
Ann. Rheum. Dis., Jun;68(6):828-35 (2009)
Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis.
Arthritis Rheum., Aug;50(8):2598-603 (2004)
Autoimmune-associated congenital heart block: dissecting the cascade from immunologic insult to relentless fibrosis.
Anat Rec A Discov Mol Cell Evol Biol., Oct;280(2):1027-35 (2004)
Autoantibody-associated congenital heart block: TGFbeta and the road to scar.
Autoimmun Rev., Jan;4(1):1-7 (2005)
Shedding of endothelial protein C receptor contributes to vasculopathy and renal injury in lupus: in vivo and in vitro evidence.
Kidney Int., Jul;68(1):110-20 (2005)
Maternal antibody responses to the 52-kd SSA/RO p200 peptide and the development of fetal conduction defects.
Arthritis Rheum., Oct;52(10):3079-86 (2005)
Cytokine polymorphisms and histologic expression in autopsy studies: contribution of TNF-alpha and TGF-beta 1 to the pathogenesis of autoimmune-associated congenital heart block.
J. Immunol., Sep;171(6):3253-61 (2003)
Autoantibody-associated congenital heart block: the clinical perspective.
Curr Rheumatol Rep., Oct;5(5):374-8 (2003)
Maternal autoantibodies and congenital heart block: mediators, markers, and therapeutic approach.
Semin. Arthritis Rheum., Dec;33(3):140-54 (2003)
Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block.
Arthritis Rheum., Jan;50(1):173-82 (2004)
More to death than dying: apoptosis in the pathogenesis of SSA/Ro-SSB/La-associated congenital heart block.
Rheum. Dis. Clin. North Am., Aug;30(3):589-602, x (2004)
Neonatal lupus: review of proposed pathogenesis and clinical data from the US-based Research Registry for Neonatal Lupus.
Autoimmunity., Feb;36(1):41-50 (2003)
Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies.
Lupus., 11(3):145-51 (2002)
Congenital heart block in neonatal lupus: the pediatric cardiologist's perspective.
Indian J Pediatr., Jun;69(6):517-22 (2002)
Long-term followup of children with neonatal lupus and their unaffected siblings.
Arthritis Rheum., Sep;46(9):2377-83 (2002)
Cardiac 5-HT(4) serotoninergic receptors, 52kD SSA/Ro and autoimmune-associated congenital heart block.
J. Autoimmun., 19(1-2):79-86 (2002)
Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block.
J. Immunol., Aug;169(4):2156-63 (2002)
Interaction between 52 kDa SSA/Ro and deubiquitinating enzyme UnpEL: a clue to function.
Int. J. Biochem. Cell Biol., Sep;33(9):924-34 (2001)
Finding the "PR-fect" Solution: What Is the Best Tool to Measure Fetal Cardiac PR Intervals for the Detection and Possible Treatment of Early Conduction Disease?
Congenit Heart Dis., Jul;7(4):349-60 (2012)
Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus.
Rheumatology (Oxford)., Jun;51(6):1086-92 (2012)
Cardiac manifestations of neonatal lupus: a review of autoantibody-associated congenital heart block and its impact in an adult population.
Cardiol Rev., 20(2):72-6 (2012)
Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside.
Nat Clin Pract Rheumatol., Mar;5(3):139-48 (2009)
Expression of endothelial protein C receptor in cortical peritubular capillaries associates with a poor clinical response in lupus nephritis.
Rheumatology (Oxford)., May;48(5):513-9 (2009)
Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel.
J. Autoimmun., Mar;34(2):80-6 (2010)
Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial.
Arthritis Rheum., Apr;62(4):1138-46 (2010)
Dying right to live longer: positing apoptosis as a link between maternal autoantibodies and congenital heart block.
Lupus., Feb;17(2):86-90 (2008)
What's in a name?
Ann. Rheum. Dis., May;67(5):732; discussion 732 (2008)
Current therapies for lupus nephritis in an ethnically heterogeneous cohort.
J. Rheumatol., Feb;36(2):298-305 (2009)
Neonatal lupus syndromes.
Lupus., 13(9):705-12 (2004)
Neonatal lupus: basic research and clinical perspectives.
Rheum. Dis. Clin. North Am., May;31(2):299-313, vii (2005)
The role of biomarkers in the assessment of lupus.
Best Pract Res Clin Rheumatol., Oct;19(5):709-26 (2005)
The presence of IgG antibodies reactive with components of the SSA/Ro-SSB/La complex in human breast milk: implications in neonatal lupus.
Arthritis Rheum., Jan;46(1):269-71 (2002)
Doppler fetal mechanical PR interval prolongation with positive maternal anti-RNP but negative SSA/Ro and SSB/La auto-antibodies
Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus
Role of the Urokinase Plasminogen Activator Receptor in Mediating Impaired Efferocytosis of Anti-SSA/Ro-Bound Apoptotic Cardiocytes: Implications in the Pathogenesis of Congenital Heart Block
Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block
The Journal of Immunology
Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial
Arthritis and Rheumatism