Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones.
J. Clin. Invest., Jun;117(6):1658-69 (2007)
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways.
J. Biol. Chem., Nov;282(48):35279-92 (2007)
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment.
J. Biol. Chem., Nov;284(45):31223-35 (2009)
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.
J. Biol. Chem., May;285(20):15333-45 (2010)
Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats.
Diabetes., May;54(5):1304-13 (2005)
Topiramate treatment causes skeletal muscle insulin sensitization and increased Acrp30 secretion in high-fat-fed male Wistar rats.
Am. J. Physiol. Endocrinol. Metab., Dec;289(6):E1015-22 (2005)
JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.
J. Biol. Chem., Oct;280(42):35361-71 (2005)
Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes.
Endocrinology., May;147(5):2245-52 (2006)
Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes.
Am. J. Physiol. Endocrinol. Metab., Jul;293(1):E219-27 (2007)
Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats.
J. Clin. Invest., Jul;114(2):224-31 (2004)
Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.
Mech. Dev., Jan;70(1-2):155-66 (1998)