Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons.
Neurobiol. Aging., Apr;33(4):827.e11-9 (2012)
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.
J. Alzheimers Dis., 26 Suppl 3:321-9 (2011)
Fluorodeoxyglucose positron emission tomography: emerging roles in the evaluation of putative Alzheimer's disease-modifying treatments.
Neurobiol. Aging., Dec;32 Suppl 1:S44-7 (2011)
Brain imaging in the study of Alzheimer's disease.
Neuroimage., Jun;61(2):505-16 (2012)
Postprandial plasma PYY concentrations are associated with increased regional gray matter volume and rCBF declines in caudate nuclei--a combined MRI and H2(15)O PET study.
Neuroimage., Mar;60(1):592-600 (2012)
Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults.
Considerations in the design of clinical trials for cognitive aging.
J. Gerontol. A Biol. Sci. Med. Sci., Jun;67(7):766-72 (2012)
Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease.
Arch. Neurol., Nov;68(11):1404-11 (2011)
Alzheimer's prevention initiative: a proposal to evaluate presymptomatic treatments as quickly as possible.
Biomark Med., Feb;4(1):3-14 (2010)
Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele.
Arch. Neurol., Apr;67(4):462-8 (2010)
Reanalysis of the obesity-related attenuation in the left dorsolateral prefrontal cortex response to a satiating meal using gyral regions-of-interest.
J Am Coll Nutr., Dec;28(6):667-73 (2009)
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Hum. Mol. Genet., Aug;19(16):3295-301 (2010)
Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEÎµ4 carriers.
Neuroimage., Feb;54(3):1896-902 (2011)
Genetic control of human brain transcript expression in Alzheimer disease.
Am. J. Hum. Genet., Apr;84(4):445-58 (2009)
Linking functional and structural brain images with multivariate network analyses: a novel application of the partial least square method.
Neuroimage., Aug;47(2):602-10 (2009)
Higher serum total cholesterol levels in late middle age are associated with glucose hypometabolism in brain regions affected by Alzheimer's disease and normal aging.
Neuroimage., Jan;49(1):169-76 (2010)
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
J Clin Psychiatry., Apr;68(4):613-8 (2007)
Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates.
Am J Psychiatry., Jun;164(6):916-21 (2007)
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Neuron., Jun;54(5):713-20 (2007)
Less activation in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal in obese than in lean women and its association with successful weight loss.
Am. J. Clin. Nutr., Sep;86(3):573-9 (2007)
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.
Physiol. Genomics., Apr;33(2):240-56 (2008)
Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions.
Neuroimage., Apr;40(3):1214-21 (2008)
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
Proc. Natl. Acad. Sci. U.S.A., Mar;105(11):4441-6 (2008)
FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice.
Int. J. Dev. Neurosci., 26(3-4):253-8 (2008)
Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.
Neurobiol. Aging., Apr;31(4):549-66 (2010)
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Neurobiol. Aging., Jun;31(6):901-9 (2010)
Relationships between plasma leptin concentrations and human brain structure: a voxel-based morphometric study.
Neurosci. Lett., Feb;412(3):248-53 (2007)
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease.
Proc. Natl. Acad. Sci. U.S.A., Apr;106(16):6820-5 (2009)
Peripheral delivery of a ROCK inhibitor improves learning and working memory.
Behav. Neurosci., Feb;123(1):218-23 (2009)
Less activation of the left dorsolateral prefrontal cortex in response to a meal: a feature of obesity.
Am. J. Clin. Nutr., Oct;84(4):725-31 (2006)
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiol. Genomics., Feb;28(3):311-22 (2007)
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment.
Mitochondrion., Dec;6(6):323-30 (2006)
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies.
Am. J. Hum. Genet., Jan;80(1):126-39 (2007)
Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans.
Neuroimage., Apr;35(2):511-7 (2007)
Linking brain imaging and genomics in the study of Alzheimer's disease and aging.
Ann. N. Y. Acad. Sci., Feb;1097:94-113 (2007)
Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance.
Hum. Mol. Genet., Jun;16(12):1469-77 (2007)
Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E Îµ4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares.
Neuroimage., May;60(4):2316-22 (2012)
Apolipoprotein E Îµ4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease.
Characterizing the Preclinical Stages of Alzheimer's Disease and the Prospect of Presymptomatic Intervention.
Amyloid-Î² assessed by florbetapir F 18 PET and 18-month cognitive decline: A multicenter study.
Neurology., Aug (2012)
Longitudinal modeling of frontal cognition in APOE Îµ4 homozygotes, heterozygotes, and noncarriers.
Neurology., Apr;76(16):1383-8 (2011)
Characterizing Alzheimer's disease using a hypometabolic convergence index.
Neuroimage., May;56(1):52-60 (2011)
Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative.
Neuroimage., Jun;51(2):654-64 (2010)
Reducing modeling error of graphical methods for estimating volume of distribution measurements in PIB-PET study.
Math Biosci., Aug;226(2):134-46 (2010)
Double-blind crossover study of the cognitive effects of lorazepam in healthy apolipoprotein E (APOE)-epsilon4 carriers.
J Clin Psychiatry., Oct;70(10):1379-84 (2009)
Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE Îµ4 allele, the major late-onset Alzheimer's susceptibility gene.
J. Alzheimers Dis., 22(1):307-13 (2010)
Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.
Arch. Neurol., Sep;64(9):1306-11 (2007)
Association between trait emotional awareness and dorsal anterior cingulate activity during emotion is arousal-dependent.
Neuroimage., Jun;41(2):648-55 (2008)
Neural correlates of heart rate variability during emotion.
Neuroimage., Jan;44(1):213-22 (2009)
Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment.
Arch. Neurol., Sep;65(9):1231-6 (2008)
Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Neuroimage., May;45(4):1107-16 (2009)
the Alzheimer's Disease Neuroimaging Initiative. Accurate measurement of brain changes in longitudinal MRI scans using tensor-based morphometry.
Cerebrovascular risk factors and preclinical memory decline in healthy APOE Îµ4 homozygotes.
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Annals of Neurology
Alzheimer's Disease Neuroimaging Initiative. Comparing predictors of conversion and decline in mild cognitive impairment.
A multi-center randomized proof-of-concept clinical trial applying [Â¹â¸F]FDG-PET for evaluation of metabolic therapy with rosiglitazone XR in mild to moderate Alzheimer's disease.
JAD: Journal of Alzheimer's Disease