What could cause secondary (acquired) immunodeficiency coupled with autoimmunity? Both started at same time. Cancers and infections?(negative 4 hiv)
Disruption of the process of self/non-self recognition can lead to either immune deficiency (increased susceptibility to infection) or to autoimmunity (increased and pathogenic responses to self-antigens).
Many of the genes that create susceptibility to autoimmunity also create susceptibility to immune deficiency.
WEAK IMMUNE SYSTEM
HUMAN IMMUNODEFICIENCY VIRUS