Gene Expression in Huntington's Disease Skeletal Muscle: a Potential Biomarker
Human Molecular Genetics
The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for The Growth and Survival of Sonic Hedgehog-induced Medulloblastomas.
p38 MAP kinase: A convergence point in cancer therapy
Trends in Molecular Medicine
Regulation of neuroD2 expression in mouse brain
Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays
Journal of Cellular Biochemistry
Cancer-specific requirement for BUB1B/BubR1 in human brain tumor isolates and genetically transformed cells.
Cancer Discov., Nov (2012)
Canonical TGF-Î² Pathway Activity Is a Predictor of SHH-Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development.
Brain Pathol., Sep (2012)
A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model.
Mol. Cell. Biol., Oct;32(20):4104-15 (2012)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Nature., Aug;488(7409):49-56 (2012)
Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Proc. Natl. Acad. Sci. U.S.A., May;109(20):7859-64 (2012)
In vivo bio-imaging using chlorotoxin-based conjugates.
Curr. Pharm. Des., Dec;17(38):4362-71 (2011)
The molecular classification of medulloblastoma: driving the next generation clinical trials.
Curr. Opin. Pediatr., Feb;24(1):33-9 (2012)
Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.
J. Clin. Oncol., Oct;29(30):3999-4006 (2011)
Personal relative deprivation, delay discounting, and gambling.
J Pers Soc Psychol., Nov;101(5):955-73 (2011)
Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo.
BMC Cancer., 11:144 (2011)
Design of highly emissive polymer dot bioconjugates for in vivo tumor targeting.
Angew. Chem. Int. Ed. Engl., Apr;50(15):3430-4 (2011)
The biological roots of complex thinking: are heritable attitudes more complex?
J Pers., Feb;79(1):101-34 (2011)
Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.
J. Med. Chem., Feb;54(3):782-7 (2011)
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
J. Clin. Oncol., Apr;29(11):1424-30 (2011)
Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease.
J. Neuropathol. Exp. Neurol., Aug;69(8):817-27 (2010)
DTI fiber tracking to differentiate demyelinating diseases from diffuse brain stem glioma.
Neuroimage., Aug;52(1):217-23 (2010)
Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation.
Mol. Cell. Neurosci., Jun;44(2):178-89 (2010)
Rapid pharmacokinetic and biodistribution studies using cholorotoxin-conjugated iron oxide nanoparticles: a novel non-radioactive method.
PLoS ONE., 5(3):e9536 (2010)
PEI-PEG-Chitosan Copolymer Coated Iron Oxide Nanoparticles for Safe Gene Delivery: synthesis, complexation, and transfection.
Adv Funct Mater., Jul;19(14):2244-2251 (2009)
DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences.
Proc. Natl. Acad. Sci. U.S.A., Jan;107(1):234-9 (2010)
Better, Stronger, Faster Self-Serving Judgment, Affect Regulation, and the Optimal Vigilance Hypothesis.
Perspect Psychol Sci., Jun;2(2):124-141 (2007)
The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.
Cancer Res., Mar;68(6):1768-76 (2008)
Self-esteem differences in the effects of hypocrisy induction on behavioral intentions in the health domain.
J Pers., Apr;76(2):305-22 (2008)
E protein dosage influences brain development more than family member identity.
J. Neurosci. Res., May;86(7):1472-81 (2008)
Relative versus absolute measures of explicit attitudes: Implications for predicting diverse attitude-relevant criteria.
J Pers Soc Psychol., Dec;93(6):907-26 (2007)
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
Cancer Genet. Cytogenet., Jan;180(1):47-50 (2008)
Response of preclinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA).
J. Neurooncol., Apr;87(2):133-41 (2008)
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration.
J. Neurosci., Oct;27(43):11758-68 (2007)
Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.
Cancer Res., Jul;67(14):6882-8 (2007)
Assessing bias in experiment design for large scale mass spectrometry-based quantitative proteomics.
Mol. Cell Proteomics., Oct;6(10):1741-8 (2007)
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Hum. Mol. Genet., Aug;16(15):1845-61 (2007)
Conservation of regional gene expression in mouse and human brain.
PLoS Genet., Apr;3(4):e59 (2007)
N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
Cancer Res., Sep;66(17):8655-61 (2006)
Congenital hypothyroidism (cretinism) in neuroD2-deficient mice.
Mol. Cell. Biol., Jun;26(11):4311-5 (2006)
Suberoylanilide hydroxamic acid is effective in preclinical studies of medulloblastoma.
J. Neurooncol., Sep;79(3):259-70 (2006)
Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data.
BMC Bioinformatics., 7:211 (2006)
A statistical method for predicting splice variants between two groups of samples using GeneChip expression array data.
Theor Biol Med Model., 3:19 (2006)
Regulation of thalamocortical patterning and synaptic maturation by NeuroD2.
Neuron., Mar;49(5):683-95 (2006)
Regional and cellular gene expression changes in human Huntington's disease brain.
Hum. Mol. Genet., Mar;15(6):965-77 (2006)
Cisplatin-based chemotherapy followed by focal, reduced-dose irradiation for pediatric primary central nervous system germinomas.
J. Pediatr. Hematol. Oncol., Jan;28(1):36-9 (2006)
Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity.
Hum. Mol. Genet., Jan;15(2):273-85 (2006)
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.
J. Neurosci., Oct;25(43):9932-9 (2005)
The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning.
Proc. Natl. Acad. Sci. U.S.A., Oct;102(41):14877-82 (2005)
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease.
Hum. Mol. Genet., Oct;14(20):3065-78 (2005)
Testing the generality of the name letter effect: name initials and everyday attitudes.
Pers Soc Psychol Bull., Aug;31(8):1099-111 (2005)
Significance testing for small microarray experiments.
Stat Med., Aug;24(15):2281-98 (2005)
Gene expression in Huntington's disease skeletal muscle: a potential biomarker.
Hum. Mol. Genet., Jul;14(13):1863-76 (2005)
A class of models for analyzing GeneChip gene expression analysis array data.
BMC Genomics., 6:16 (2005)
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas.
Cancer Res., Nov;64(21):7794-800 (2004)
The vulnerability of values to attack: inoculation of values and value-relevant attitudes.
Pers Soc Psychol Bull., Jan;29(1):63-75 (2003)
Framing social judgment: self-ingroup comparison and perceived discrimination.
Pers Soc Psychol Bull., Feb;29(2):228-36 (2003)
p38 MAP kinase: a convergence point in cancer therapy.
Trends Mol Med., Mar;10(3):125-9 (2004)
Regulation of neuroD2 expression in mouse brain.
Dev. Biol., Jan;265(1):234-45 (2004)
An analysis of empirical research on the scope of justice.
Pers Soc Psychol Rev., 7(4):311-23 (2003)
Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays.
J. Cell. Biochem., Dec;90(5):1068-78 (2003)
Linkage analysis of human systemic lupus erythematosus-related traits: a principal component approach.
Arthritis Rheum., Dec;44(12):2807-18 (2001)