Activation of notch signaling during ex vivo expansion maintains donor muscle cell engraftment.
Stem Cells., Oct;30(10):2212-20 (2012)
Correlation of CD33 expression level with disease characteristics and response to gemtuzumab ozogamicin containing chemotherapy in childhood AML.
Blood., Apr;119(16):3705-11 (2012)
Engineering stem cell expansion.
Cell Stem Cell., Feb;10(2):113-4 (2012)
Acute myeloid leukemia stem cells and CD33-targeted immunotherapy.
Blood., Jun;119(26):6198-208 (2012)
SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.
Blood., Feb;119(8):1856-60 (2012)
Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG.
Blood., Oct;118(17):4561-6 (2011)
AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.
Blood., Aug;118(7):1784-96 (2011)
Ex vivo expansion of human hematopoietic stem and progenitor cells.
Blood., Jun;117(23):6083-90 (2011)
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.
Blood., Apr;117(17):4449-59 (2011)
Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.
J. Clin. Invest., Mar;121(3):1207-16 (2011)
Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells.
Blood., Dec;116(26):5859-66 (2010)
Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.
Leukemia., May;24(5):909-13 (2010)
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Cell Stem Cell., Mar;6(3):251-64 (2010)
Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.
Nat. Med., Feb;16(2):232-6 (2010)
Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.
Blood., Mar;115(12):2372-9 (2010)
Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.
Blood., Jan;115(4):757-65 (2010)
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.
Cell Stem Cell., Dec;3(6):611-24 (2008)
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
J. Immunol., Nov;181(9):5885-94 (2008)
Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.
Genes Dev., Jun;22(12):1677-89 (2008)
Simultaneously targeting CD45 significantly increases cytotoxicity of the anti-CD33 immunoconjugate, gemtuzumab ozogamicin, against acute myeloid leukemia (AML) cells and improves survival of mice bearing human AML xenografts.
Blood., May;111(9):4813-6 (2008)