G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.
Proc. Natl. Acad. Sci. U.S.A., Dec (2012)
HDAC6 Regulates Epidermal Growth Factor Receptor (EGFR) Endocytic Trafficking and Degradation in Renal Epithelial Cells.
PLoS ONE., 7(11):e49418 (2012)
Role of genetic modifiers in an orthologous rat model of ARPKD.
Physiol. Genomics., Aug;44(15):741-53 (2012)
Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease".
Am. J. Physiol., Cell Physiol., May;302(10):C1434-5 (2012)
Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents.
FASEB J., Jun;25(6):1844-55 (2011)
Diagnosis and management of childhood polycystic kidney disease.
Pediatr. Nephrol., May;26(5):675-92 (2011)
Birth of a healthy infant following preimplantation PKHD1 haplotyping for autosomal recessive polycystic kidney disease using multiple displacement amplification.
J. Assist. Reprod. Genet., Jul;27(7):397-407 (2010)
Polycystic Kidney Disease, Autosomal Recessive
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.
Am. J. Physiol. Renal Physiol., Sep;297(3):F662-70 (2009)
Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD.
Am. J. Physiol. Renal Physiol., Mar;296(3):F575-82 (2009)
20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease.
J. Am. Soc. Nephrol., Oct;19(10):1929-39 (2008)
Src inhibition ameliorates polycystic kidney disease.
J. Am. Soc. Nephrol., Jul;19(7):1331-41 (2008)
Renal cystic disease: new insights for the clinician.
Pediatr. Clin. North Am., Oct;53(5):889-909, ix (2006)
Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference.
J. Pediatr., Aug;149(2):159-64 (2006)
Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD).
Cell Tissue Res., Dec;326(3):671-85 (2006)
Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease.
Am. J. Kidney Dis., Jan;45(1):77-87 (2005)
Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats.
Kidney Int., Nov;66(5):1766-73 (2004)
EGF-related growth factors in the pathogenesis of murine ARPKD.
Kidney Int., Jun;65(6):2018-29 (2004)
Survival of childhood polycystic kidney disease following renal transplantation: the impact of advanced hepatobiliary disease.
Pediatr Transplant., Oct;7(5):364-9 (2003)
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
Kidney Int., Nov;64(5):1573-9 (2003)
The molecular biology of polycystic kidney disease.
Pediatr. Nephrol., Nov;12(9):721-6 (1998)
PKD and CF: an interesting family provides insight into the molecular pathophysiology of polycystic kidney disease.
Am. J. Kidney Dis., Dec;32(6):1081-3 (1998)
Morphological and functional characterization of a conditionally immortalized collecting tubule cell line.
Am. J. Physiol., Nov;275(5 Pt 2):F802-11 (1998)
Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease.
Am. J. Physiol., Sep;275(3 Pt 2):F387-94 (1998)
Cell and molecular biology of kidney development.
Semin. Nephrol., May;18(3):233-43 (1998)
The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development.
In Vitro Cell. Dev. Biol. Anim., Feb;34(2):189-94 (1998)
Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.
J. Clin. Invest., Mar;101(5):935-9 (1998)
Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology.
Am. J. Med. Genet., Mar;76(2):137-44 (1998)
Efficacy of taxol in the orpk mouse model of polycystic kidney disease.
Pediatr. Nephrol., Dec;11(6):728-33 (1997)
Improved outcome of young children on nightly automated peritoneal dialysis.
Pediatr. Nephrol., Dec;11(6):676-9 (1997)
Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion.
Am. J. Pathol., Jun;150(6):2231-41 (1997)
An integrated genetic and physical map of the autosomal recessive polycystic kidney disease region.
Genomics., May;41(3):463-6 (1997)
Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.
Kidney Int., Oct;50(4):1240-8 (1996)
Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic.
Kidney Int., Oct;50(4):1158-65 (1996)
Novel Madin Darby canine kidney cell clones exhibit unique phenotypes in response to morphogens.
In Vitro Cell. Dev. Biol. Anim., Jun;32(6):329-39 (1996)
Alternate-day steroid dosing improves growth without adversely affecting graft survival or long-term graft function. A report of the North American Pediatric Renal Transplant Cooperative Study.
Transplantation., Jan;61(1):31-6 (1996)
Clinical quiz. Differential diagnosis of a patient with Wegener's granulomatosis.
Pediatr. Nephrol., Dec;9(6):785-7 (1995)
Congenital nephropathies and uropathies.
Pediatr. Clin. North Am., Dec;42(6):1319-41 (1995)
1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development.
Am. J. Physiol., Sep;269(3 Pt 2):F419-28 (1995)
Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis.
J. Am. Soc. Nephrol., Aug;6(2):269-72 (1995)
Cystic maldevelopment of the kidney.
Semin. Nephrol., Jul;15(4):341-52 (1995)
Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor.
Pediatr. Res., Jun;37(6):755-63 (1995)
The severe perinatal form of autosomal recessive polycystic kidney disease maps to chromosome 6p21.1-p12: implications for genetic counseling.
Am. J. Hum. Genet., May;56(5):1101-7 (1995)
Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture.
Kidney Int., Mar;47(3):774-81 (1995)
Renal transplantation and chronic dialysis in children and adolescents: the 1993 annual report of the North American Pediatric Renal Transplant Cooperative Study.
Pediatr. Nephrol., Feb;9(1):61-73 (1995)
Epidermal growth factor receptor expression is abnormal in murine polycystic kidney.
Kidney Int., Feb;47(2):490-9 (1995)
Gene time for polycystic kidney disease.
Lancet., Sep;344(8926):833-4 (1994)
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.
Science., May;264(5163):1329-33 (1994)
Renal developmental diseases.
Semin. Nephrol., Sep;13(5):427-35 (1993)
Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease.
Pediatr. Nephrol., Apr;7(2):163-72 (1993)
A new murine model of autosomal recessive polycystic kidney disease.
Nihon Jinzo Gakkai Shi., Apr;35(4):349-54 (1993)
Normal and abnormal nephrogenesis.
Am. J. Kidney Dis., Jan;21(1):64-70 (1993)
Epithelial polarity and differentiation in polycystic kidney disease.
J. Cell Sci. Suppl., 17:217-22 (1993)
The case against screening urinalyses for asymptomatic bacteriuria in children.
Am. J. Dis. Child., Mar;146(3):343-6 (1992)
Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease.
Contrib Nephrol., 97:23-34 (1992)
Inherited polycystic kidney disease in children.
Semin. Nephrol., Nov;11(6):632-42 (1991)
Localization of arginine biosynthetic enzymes in renal proximal tubules and abundance of mRNA during development.
Pediatr. Res., Feb;29(2):151-4 (1991)
Polypeptide growth factors in metanephric growth and segmental nephron differentiation.
Pediatr. Nephrol., Jul;4(4):372-7 (1990)
Polypeptide growth factors and the kidney: a developmental perspective.
Pediatr. Nephrol., Jul;4(4):345-53 (1990)
In vitro modulation of tubular cyst regression in murine polycystic kidney disease.
Kidney Int., Dec;36(6):960-8 (1989)
Regulation of glucocorticoid receptors and Na-K ATPase activity by hydrocortisone in proximal tubular epithelial cells.
In Vitro Cell. Dev. Biol., Aug;24(8):811-6 (1988)
Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation.
Pediatr. Nephrol., Apr;2(2):210-8 (1988)
Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.
J. Histochem. Cytochem., Feb;36(2):159-66 (1988)
Renal cystic disease. Insights from recent experimental investigations.
Nephron., 48(2):89-93 (1988)
Renal epithelial development in organotypic culture.
Pediatr. Nephrol., Jan;2(1):92-9 (1988)
Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation.
Pediatr. Nephrol., Oct;1(4):587-96 (1987)
Glucocorticoids modulate renal glucocorticoid receptors and Na-K ATPase activity.
Kidney Int., Oct;32(4):464-71 (1987)
Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.
J. Lab. Clin. Med., Apr;109(4):441-53 (1987)
Reversible inhibition of cytosolic glucocorticoid receptors by mercurial agents. Application in the measurement of total and unoccupied receptors.
J. Recept. Res., 7(5):761-74 (1987)
Renal failure and dialysis therapy in children with hepatic failure in the perioperative period of orthotopic liver transplantation.
Clin. Nephrol., Jun;25(6):295-303 (1986)
Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney.
J. Steroid Biochem., May;24(5):997-1003 (1986)
Renal failure in children with hepatic failure undergoing liver transplantation.
J. Pediatr., Mar;108(3):393-8 (1986)
Regression of genetically determined polycystic kidney disease in murine organ culture.
Experientia., Jan;42(1):77-80 (1986)