Dr. John Griffin
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Dr. John Griffin
Dr. John Griffin
Internal Medicine - Rheumatology
I specialize in
Internal Medicine - Rheumatology
I have been in practice
My answers and insights have
Helped 20 people
Here are kind words from others
This Thanksgiving, I wanted to share my appreciation for all that you do! Thank you, doctor! :)
I am located at
10101 SE Main St Ste 2001
Portland , OR 97216
Accepted Insurance Plans
I was educated and trained at
Medical / Graduate School
Loma Linda University School of Medicine
A novel system to accelerate the progression of nerve degeneration in transgenic mouse models of neuropathies.
Exp. Neurol., Sep;237(1):153-9 (2012)
The lateral thoracic nerve and the cutaneous maximus muscle--a novel in vivo model system for nerve degeneration and regeneration studies.
Exp. Neurol., Jul;236(1):6-18 (2012)
Diabetes and employment.
Diabetes Care., Jan;35 Suppl 1:S94-8 (2012)
Diabetes and driving.
Diabetes Care., Jan;35 Suppl 1:S81-6 (2012)
Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system.
J. Neurosci., Apr;31(15):5744-54 (2011)
Passive transfer of IgG anti-GM1 antibodies impairs peripheral nerve repair.
J. Neurosci., Jul;30(28):9533-41 (2010)
Myelin-associated glycoprotein (MAG) protects neurons from acute toxicity using a ganglioside-dependent mechanism.
ACS Chem Neurosci., Mar;1(3):215-222 (2010)
Measuring nerve regeneration in the mouse.
Exp. Neurol., May;223(1):60-71 (2010)
Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy.
J. Neurosci., Mar;29(10):3160-71 (2009)
Intravenous immunoglobulin for neuromuscular disease: costs, benefits and reimbursement.
Nat Clin Pract Neurol., Mar;5(3):119 (2009)
The gathering storm.
Nat Clin Pract Neurol., Feb;5(2):61 (2009)
Peripheral nerve vasculitis presenting as complex regional pain syndrome.
J Clin Neuromuscul Dis., Dec;10(2):61-4 (2008)
Impaired synaptic vesicle release and immaturity of neuromuscular junctions in spinal muscular atrophy mice.
J. Neurosci., Jan;29(3):842-51 (2009)
Axonal protective effects of the myelin-associated glycoprotein.
J. Neurosci., Jan;29(3):630-7 (2009)
beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones.
Mol Brain., 1:10 (2008)
Biology and pathology of nonmyelinating Schwann cells.
Glia., Nov;56(14):1518-31 (2008)
Behavioral and pathological outcomes in MOG 35-55 experimental autoimmune encephalomyelitis.
J. Neuroimmunol., Aug;199(1-2):83-93 (2008)
Diagnostic nerve biopsy: a case history.
Nat Clin Pract Neurol., Apr;4(4):175 (2008)
Comparison of cytokine expression profile during Wallerian degeneration of myelinated and unmyelinated peripheral axons.
Neurosci. Lett., Jan;430(3):230-5 (2008)
Cleavage of myelin associated glycoprotein by matrix metalloproteinases.
J. Neuroimmunol., Jan;193(1-2):140-8 (2008)
You can't cure a disease by throwing money at it, can you?
Nat Clin Pract Neurol., Oct;3(10):531 (2007)
Patterns of Guillain-Barre syndrome in children: results from a Mexican population.
Neurology., Oct;69(17):1665-71 (2007)
Denervation of skin in neuropathies: the sequence of axonal and Schwann cell changes in skin biopsies.
Brain., Oct;130(Pt 10):2703-14 (2007)
Anti-ganglioside antibodies alter presynaptic release and calcium influx.
Neurobiol. Dis., Oct;28(1):113-21 (2007)
Augustus Waller and the case of the disappearing axon.
Nat Clin Pract Neurol., Jul;3(7):355 (2007)
A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.
Neuron., Jun;54(5):739-54 (2007)
Academic neurology and industry: open doors or firewalls?
Nat Clin Pract Neurol., Jun;3(6):297 (2007)
Academic medicine and the home: work and life in the balance.
Nat Clin Pract Neurol., Feb;3(2):59 (2007)
Training for tomorrow's brain sciences.
Nat Clin Pract Neurol., Dec;2(12):637 (2006)
Activity-dependent slowing of conduction velocity in uninjured L4 C fibers increases after an L5 spinal nerve injury in the rat.
Pain., Mar;128(1-2):40-51 (2007)
Teaching and learning empathy.
Nat Clin Pract Neurol., Oct;2(10):517 (2006)
Research in neurological diseases: lost in translation?
Nat Clin Pract Neurol., Feb;2(2):59 (2006)
Neurologists don't do windows.
Nat Clin Pract Neurol., Jan;2(1):1 (2006)
Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients.
Neurology., Aug;67(3):383-8 (2006)
Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice.
Exp. Neurol., Sep;195(1):208-17 (2005)
Overlap of pathology in paralytic rabies and axonal Guillain-Barre syndrome.
Ann. Neurol., May;57(5):768-72 (2005)
Degeneration of myelinated efferent fibers prompts mitosis in Remak Schwann cells of uninjured C-fiber afferents.
J. Neurosci., Feb;25(5):1179-87 (2005)
Another tool for the neurologist's toolbox.
Ann. Neurol., Feb;57(2):163-7 (2005)
Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves.
Exp. Neurol., Oct;189(2):231-40 (2004)
An anti-ganglioside antibody-secreting hybridoma induces neuropathy in mice.
Ann. Neurol., Aug;56(2):228-39 (2004)
The time course of epidermal nerve fibre regeneration: studies in normal controls and in people with diabetes, with and without neuropathy.
Brain., Jul;127(Pt 7):1606-15 (2004)
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4).
Am. J. Hum. Genet., Jun;74(6):1128-35 (2004)
Anti-ganglioside antibody-mediated neuronal cytotoxicity and its protection by intravenous immunoglobulin: implications for immune neuropathies.
Brain., May;127(Pt 5):1085-100 (2004)
Severity and duration of hyperalgesia in rat varies with type of nerve lesion.
Neurosurgery., Nov;53(5):1200-8; discussion 1208-9 (2003)
Variants of the Guillain BarrÃ© syndrome: progress toward fulfilling "Koch's postulates".
Ann. Neurol., Jun;49(6):694-6 (2001)
Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-BarrÃ© syndrome.
Ann. Neurol., Feb;45(2):168-73 (1999)
Epidermal nerve fiber density: normative reference range and diagnostic efficiency.
Arch. Neurol., Dec;55(12):1513-20 (1998)
Campylobacter jejuni lipopolysaccharides in Guillain-BarrÃ© syndrome: molecular mimicry and host susceptibility.
Neurology., Aug;51(2):371-8 (1998)
Molecular mimicry in Guillain-BarrÃ© syndrome.
Ann. N. Y. Acad. Sci., Jun;845:307-21 (1998)
Human autoimmune neuropathies.
Annu. Rev. Neurosci., 21:187-226 (1998)
Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection.
Neurology., Mar;48(3):717-24 (1997)
Immune attack on the Schwann cell surface in acute inflammatory demyelinating polyneuropathy.
Ann. Neurol., May;39(5):625-35 (1996)
Laboratory testing in peripheral nerve disease.
Neurol Clin., Feb;14(1):119-33 (1996)
Pathology of the motor-sensory axonal Guillain-BarrÃ© syndrome.
Ann. Neurol., Jan;39(1):17-28 (1996)
Antiviral activity of alpha interferon in Sindbis virus-infected cells is restored by anti-E2 monoclonal antibody treatment.
J. Virol., Nov;69(11):7345-8 (1995)
Effects of anti-E2 monoclonal antibody on sindbis virus replication in AT3 cells expressing bcl-2.
J. Virol., Nov;69(11):7006-14 (1995)
Guillain-BarrÃ© syndrome in northern China. Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies.
Brain., Jun;118 ( Pt 3):597-605 (1995)
Antiglycolipid antibodies and peripheral neuropathies: links to pathogenesis.
Prog. Brain Res., 101:313-23 (1994)
Expression of NGF-receptors during immune-mediated and lysolecithin-induced demyelination of the peripheral nervous system.
J. Neurocytol., Dec;22(12):1022-9 (1993)
Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia.
Ann. Neurol., Jun;33(6):576-82 (1993)
Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination.
J. Neuroimmunol., Oct;40(2-3):153-65 (1992)
Cytokine expression in the brain during the acquired immunodeficiency syndrome.
Ann. Neurol., Apr;31(4):349-60 (1992)
Regulation of aberrant neurofilament phosphorylation in neuronal perikarya. II. Correlation with continued axonal elongation following axotomy.
J. Neuropathol. Exp. Neurol., Sep;50(5):627-48 (1991)
Inflammatory demyelinating polyneuropathy in a child with symptomatic human immunodeficiency virus infection.
J. Pediatr., Feb;118(2):242-5 (1991)
Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies.
Ann. Neurol., Mar;27(3):316-26 (1990)
Macrophage responses in inflammatory demyelinating neuropathies.
Ann. Neurol., 27 Suppl:S64-8 (1990)
Anti-GM1 ganglioside antibodies with differing fine specificities in patients with multifocal motor neuropathy.
J. Neuroimmunol., Dec;25(2-3):143-50 (1989)
Phosphorylation-dependent immunoreactivity of neurofilaments increases during axonal maturation and beta,beta'-iminodipropionitrile intoxication.
J. Neurochem., Dec;53(6):1818-29 (1989)
Astrocytes and Schwann cells are virus-host cells in the nervous system of rats with Borna disease.
J. Neuropathol. Exp. Neurol., Nov;48(6):631-44 (1989)
Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression.
J. Neurosci., Jul;9(7):2327-35 (1989)
Demyelination induced by intraneural injection of human antimyelin-associated glycoprotein antibodies.
Muscle Nerve., Nov;11(11):1169-76 (1988)
A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside.
Ann. Neurol., Jul;24(1):73-8 (1988)
Serum antibodies to gangliosides in Guillain-BarrÃ© syndrome.
Ann. Neurol., May;23(5):440-7 (1988)
Neurofilament antigens in acrylamide neuropathy.
J. Neuropathol. Exp. Neurol., Mar;47(2):145-57 (1988)
Pathogenesis of Borna disease in rats: evidence that intra-axonal spread is the major route for virus dissemination and the determinant for disease incubation.
J. Virol., Nov;61(11):3431-40 (1987)
Characterization of antineurofilament autoantibodies in Creutzfeldt-Jakob disease.
J. Neuropathol. Exp. Neurol., Jul;43(4):369-75 (1984)
Immunocytochemical localization of tetanus toxin to synapses of spinal cord.
Neurosci. Lett., May;23(2):149-55 (1981)
Dr. John Griffin M