Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.
PLoS ONE., 7(9):e44241 (2012)
Phage Display-directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication.
Mol. Ther., Nov;20(11):2064-75 (2012)
Isolation of monoclonal antibodies with predetermined conformational epitope specificity.
PLoS ONE., 7(6):e38943 (2012)
Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaques during disease progression analyzed by ultra-deep pyrosequencing.
PLoS ONE., 7(3):e32827 (2012)
No acquisition: a new ambition for HIV vaccine development?
Curr Opin Virol., Oct;1(4):246-53 (2011)
Efficiency of neutralizing antibodies targeting the CD4-binding site: influence of conformational masking by the V2 loop in R5-tropic clade C simian-human immunodeficiency virus.
J. Virol., Dec;85(23):12811-4 (2011)
High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia.
AIDS., Jan;26(2):149-55 (2012)
Molecularly cloned SHIV-CN97001: a replication-competent, R5 simian/human immunodeficiency virus containing env of a primary Chinese HIV-1 clade C isolate.
J. Med. Primatol., Dec;40(6):427-36 (2011)
Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 Clade C SHIV.
PLoS Negl Trop Dis., Aug;5(8):e1270 (2011)
Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.
PLoS ONE., 6(7):e22010 (2011)
Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.
Vaccine., Aug;29(34):5611-22 (2011)
An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV.
PLoS ONE., 6(3):e18207 (2011)
R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.
PLoS ONE., 6(4):e18465 (2011)
Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV.
J Immune Based Ther Vaccines., 9:2 (2011)
A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly.
Vaccine., Jan;29(3):476-86 (2011)
Development of a tier 1 R5 clade C simian-human immunodeficiency virus as a tool to test neutralizing antibody-based immunoprophylaxis.
J. Med. Primatol., Apr;40(2):120-8 (2011)
R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.
PLoS ONE., 5(7):e11689 (2010)
Bimodal AIDS vaccine approach: induction of cellular as well as humoral immunity can protect from systemic infection.
Vaccine., May;28 Suppl 2:B25-31 (2010)
AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4.
J. Med. Primatol., Oct;39(5):356-60 (2010)
Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes.
J. Infect. Dis., Apr;201(8):1155-63 (2010)