Human immunodeficiency virus vaccine trials.
Cold Spring Harb Perspect Med., 2(12) (2012)
A Sequential Phase 2b Trial Design for Evaluating Vaccine Efficacy and Immune Correlates for Multiple HIV Vaccine Regimens.
Stat Commun Infect Dis., Oct;3(1) (2011)
MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load.
PLoS ONE., 7(8):e43396 (2012)
Changes in the soluble mucosal immune environment during genital herpes outbreaks.
J. Acquir. Immune Defic. Syndr., Oct;61(2):194-202 (2012)
An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection.
J. Virol., Oct;86(19):10587-96 (2012)
A prospective cohort study of partner testing for herpes simplex virus and sexual behavior during pregnancy.
J. Infect. Dis., Aug;206(4):486-94 (2012)
Efficacy of a viral load-based, risk-adapted, preemptive treatment strategy for prevention of cytomegalovirus disease after hematopoietic cell transplantation.
Biol. Blood Marrow Transplant., Nov;18(11):1687-99 (2012)
Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (Step Study).
J. Infect. Dis., Jul;206(2):258-66 (2012)
Decreased pre-existing Ad5 capsid and Ad35 neutralizing antibodies increase HIV-1 infection risk in the Step trial independent of vaccination.
PLoS ONE., 7(4):e33969 (2012)
Efficiency and risk factors for CMV transmission in seronegative hematopoietic stem cell recipients.
Biol. Blood Marrow Transplant., Sep;18(9):1391-400 (2012)
Cytomegalovirus viremia as a risk factor for mortality prior to antiretroviral therapy among HIV-infected gold miners in South Africa.
PLoS ONE., 6(10):e25571 (2011)
Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study).
J. Acquir. Immune Defic. Syndr., Jul;57(3):238-44 (2011)
Treatment with valacyclovir, famciclovir, or antiretrovirals reduces human herpesvirus-8 replication in HIV-1 seropositive men.
J. Med. Virol., Oct;83(10):1696-703 (2011)
Development of an interferon-gamma ELISPOT assay to detect human T cell responses to HSV-2.
Vaccine., Sep;29(40):7058-66 (2011)
The kinetics of mucosal herpes simplex virus-2 infection in humans: evidence for rapid viral-host interactions.
J. Infect. Dis., Aug;204(4):554-61 (2011)
Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step study.
PLoS ONE., 6(6):e20479 (2011)
Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study.
Lancet Infect Dis., Jul;11(7):507-15 (2011)
Genital HSV detection among HIV-1-infected pregnant women in labor.
Infect Dis Obstet Gynecol., 2011:157680 (2011)
HIV-1 vaccines and adaptive trial designs.
Sci Transl Med., Apr;3(79):79ps13 (2011)
Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy.
J. Infect. Dis., May;203(10):1474-83 (2011)
Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection.
JAMA., Apr;305(14):1441-9 (2011)
H275Y mutant pandemic (H1N1) 2009 virus in immunocompromised patients.
Emerging Infect. Dis., Apr;17(4):653-60; quiz 765 (2011)
HIV-specific CD8+ T cells from HIV+ individuals receiving HAART can be expanded ex vivo to augment systemic and mucosal immunity in vivo.
Blood., May;117(20):5391-402 (2011)
The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro.
Antimicrob. Agents Chemother., Jun;55(6):2696-703 (2011)
Introduction of a novel parechovirus RT-PCR clinical test in a regional medical center.
J. Clin. Virol., May;51(1):50-3 (2011)
Differences in clinical outcomes after 2009 influenza A/H1N1 and seasonal influenza among hematopoietic cell transplant recipients.
Blood., May;117(19):5050-6 (2011)
Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial.
Nat. Med., Mar;17(3):366-71 (2011)
Persistence in the population: epidemiology, transmission
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. (2007)
Persistent genital herpes simplex virus-2 shedding years following the first clinical episode.
J. Infect. Dis., Jan;203(2):180-7 (2011)
Serological immunity to adenovirus serotype 5 is not associated with risk of HIV infection: a case-control study.
AIDS., Jan;25(2):153-8 (2011)
Gender differences in clinical presentation and outcomes of epidemic Kaposi sarcoma in Uganda.
PLoS ONE., 5(11):e13936 (2010)
Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes.
Proc. Natl. Acad. Sci. U.S.A., Nov;107(44):18973-8 (2010)
Cervicovaginal shedding of hepatitis C viral RNA is associated with the presence of menstrual or other blood in cervicovaginal fluids.
J. Clin. Virol., Jan;50(1):4-7 (2011)
Impact of corticosteroid treatment and antiviral therapy on clinical outcomes in hematopoietic cell transplant patients infected with influenza virus.
Biol. Blood Marrow Transplant., Jul;17(7):979-86 (2011)
Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes.
J. Clin. Immunol., Sep;30(5):703-22 (2010)
Subclinical viremia increases risk for chronic allograft injury in pediatric renal transplantation.
J. Am. Soc. Nephrol., Sep;21(9):1579-86 (2010)
Frequent detection of human adenovirus from the lower gastrointestinal tract in men who have sex with men.
PLoS ONE., 5(6):e11321 (2010)
Rapid polymerase chain reaction assay to detect herpes simplex virus in the genital tract of women in labor.
Obstet Gynecol., Jun;115(6):1209-16 (2010)
Population level impact of an imperfect prophylactic vaccine for herpes simplex virus-2.
Sex Transm Dis., May;37(5):290-7 (2010)
HIV vaccines: mosaic approach to virus diversity.
Nat. Med., Mar;16(3):268-70 (2010)
Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children.
Pediatr Blood Cancer., May;54(5):670-4 (2010)
Detailed characterization of T cell responses to herpes simplex virus-2 in immune seronegative persons.
J. Immunol., Mar;184(6):3250-9 (2010)
Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model.
Sci Transl Med., Nov;1(7):7ra16 (2009)
In situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques.
Retrovirology., 7:12 (2010)
In memoriam: Walter E. Stamm.
J. Infect. Dis., Mar;201(5):645-6 (2010)
Overlapping reactivations of herpes simplex virus type 2 in the genital and perianal mucosa.
J. Infect. Dis., Feb;201(4):499-504 (2010)
Inadequacy of plasma acyclovir levels at delivery in patients with genital herpes receiving oral acyclovir suppressive therapy in late pregnancy.
J Obstet Gynaecol Can., Dec;31(12):1137-43 (2009)
Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients.
Blood., Mar;115(10):2088-94 (2010)
New concepts in understanding genital herpes.
Curr Infect Dis Rep., Nov;11(6):457-64 (2009)
Hepatitis C virus is infrequently evaluated and treated in an urban HIV clinic population.
AIDS Patient Care STDS., Nov;23(11):925-9 (2009)
Clinical correlates of herpes simplex virus viremia among hospitalized adults.
Clin. Infect. Dis., Nov;49(9):1295-301 (2009)
Maternal and neonatal herpes simplex virus infections.
N. Engl. J. Med., Oct;361(14):1376-85 (2009)
Evasion of the mucosal innate immune system by herpes simplex virus type 2.
J. Virol., Dec;83(23):12559-68 (2009)
Preinfection human immunodeficiency virus (HIV)-specific cytotoxic T lymphocytes failed to prevent HIV type 1 infection from strains genetically unrelated to viruses in long-term exposed partners.
J. Virol., Oct;83(20):10821-9 (2009)
Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition.
Nat. Med., Aug;15(8):886-92 (2009)
Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation.
Haematologica., Aug;94(8):1101-8 (2009)
Effect of conditioning regimen intensity on CMV infection in allogeneic hematopoietic cell transplantation.
Biol. Blood Marrow Transplant., Jun;15(6):694-703 (2009)
Gram-negative bloodstream infections in hematopoietic stem cell transplant patients: the roles of needleless device use, bathing practices, and catheter care.
Am J Infect Control., May;37(4):327-34 (2009)
Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study.
PLoS ONE., 4(4):e5272 (2009)
Vaccine prevention of maternal cytomegalovirus infection.
N. Engl. J. Med., Mar;360(12):1191-9 (2009)
The acceptance of HSV-testing partners of HSV-2 seronegative pregnant women.
Sex Transm Dis., Apr;36(4):211-5 (2009)
HSV suppression reduces seminal HIV-1 levels in HIV-1/HSV-2 co-infected men who have sex with men.
AIDS., Feb;23(4):479-83 (2009)
Impact of HIV infection and Kaposi sarcoma on human herpesvirus-8 mucosal replication and dissemination in Uganda.
PLoS ONE., 4(1):e4222 (2009)
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis.
Lancet., Nov;372(9653):1894-905 (2008)
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial.
Lancet., Nov;372(9653):1881-93 (2008)
Safety and immunogenicity of a CTL multiepitope peptide vaccine for HIV with or without GM-CSF in a phase I trial.
Vaccine., Jan;27(2):243-9 (2009)
Cytomegalovirus reactivation in critically ill immunocompetent patients.
JAMA., Jul;300(4):413-22 (2008)
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial.
Lancet., Jun;371(9630):2109-19 (2008)
Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa.
PLoS ONE., 3(5):e2230 (2008)
Herpes simplex virus viremia during primary genital infection.
J. Infect. Dis., Jul;198(1):31-4 (2008)
Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV).
AIDS Res. Hum. Retroviruses., Apr;24(4):561-71 (2008)
Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses.
Virology., May;374(2):229-33 (2008)
Gamma delta+ T cells involvement in viral immune control of chronic human herpesvirus 8 infection.
J. Immunol., Mar;180(5):3417-25 (2008)
Herpes simplex: insights on pathogenesis and possible vaccines.
Annu. Rev. Med., 59:381-95 (2008)
Blood monocytes harbor HIV type 1 strains with diversified phenotypes including macrophage-specific CCR5 virus.
J. Infect. Dis., Jan;197(2):309-18 (2008)
Herpes simplex virus (HSV) suppression with valacyclovir reduces rectal and blood plasma HIV-1 levels in HIV-1/HSV-2-seropositive men: a randomized, double-blind, placebo-controlled crossover trial.
J. Infect. Dis., Nov;196(10):1500-8 (2007)
Antimicrobial resistance prevention initiative--an update: proceedings of an expert panel on resistance.
Am J Infect Control., Nov;35(9):S1-23; quiz S24-6 (2007)
A framework for assessing immunological correlates of protection in vaccine trials.
J. Infect. Dis., Nov;196(9):1304-12 (2007)
Does frequency of genital herpes recurrences predict risk of transmission? Further analysis of the valacyclovir transmission study.
Sex Transm Dis., Feb;35(2):124-8 (2008)
An update on short-course intermittent and prevention therapies for herpes labialis.
Herpes., Jun;14 Suppl 1:13A-18A (2007)
An update on short-course episodic and prevention therapies for herpes genitalis.
Herpes., Jun;14 Suppl 1:5A-11A (2007)
Quantitative real-time polymerase chain reaction for detection of adenovirus after T cell-replete hematopoietic cell transplantation: viral load as a marker for invasive disease.
Clin. Infect. Dis., Oct;45(8):958-65 (2007)
Antimicrobial resistance prevention initiative--an update: proceedings of an expert panel on resistance.
Am. J. Med., Jul;120(7):S4-25; quiz S26-8 (2007)
Safety and tolerability of oseltamivir prophylaxis in hematopoietic stem cell transplant recipients: a retrospective case-control study.
Clin. Infect. Dis., Jul;45(2):187-93 (2007)
Adolescents are more likely to develop posttransplant lymphoproliferative disorder after primary Epstein-Barr virus infection than younger renal transplant recipients.
Transplantation., Jun;83(11):1423-8 (2007)
Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection.
Blood., Sep;110(5):1681-8 (2007)
Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus.
J. Infect. Dis., Jun;195(12):1762-4 (2007)
Longitudinal study of herpes simplex virus type 2 infection using viral dynamic modelling.
Sex Transm Infect., Aug;83(5):359-64 (2007)
Effect of maternal herpes simplex virus (HSV) serostatus and HSV type on risk of neonatal herpes.
Acta Obstet Gynecol Scand., 86(5):523-9 (2007)
Topical resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trial.
J. Infect. Dis., May;195(9):1324-31 (2007)
Herpes simplex virus type 2 and HIV-1: the dialogue between the 2 organisms continues.
J. Infect. Dis., May;195(9):1242-4 (2007)
Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation.
J. Exp. Med., Mar;204(3):595-603 (2007)
Herpes simplex virus type 2 and risk of intrapartum human immunodeficiency virus transmission.
Obstet Gynecol., Feb;109(2 Pt 1):403-9 (2007)
HIV-1 CTL-based vaccine immunogen selection: antigen diversity and cellular response features.
Curr. HIV Res., Jan;5(1):97-107 (2007)
Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes.
Am. J. Pathol., Feb;170(2):478-89 (2007)
Frequent and asymptomatic oropharyngeal shedding of human herpesvirus 8 among immunocompetent men.
J. Infect. Dis., Jan;195(1):30-6 (2007)
Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.
J. Acquir. Immune Defic. Syndr., Feb;44(2):203-12 (2007)
Continued evolution of HIV-1 circulating in blood monocytes with antiretroviral therapy: genetic analysis of HIV-1 in monocytes and CD4+ T cells of patients with discontinued therapy.
J. Leukoc. Biol., Nov;80(5):1118-26 (2006)
Polymerase chain reaction diagnosis of primary human herpesvirus-6 infection in the acute care setting.
J. Pediatr., Oct;149(4):480-5 (2006)
Selection on the human immunodeficiency virus type 1 proteome following primary infection.
J. Virol., Oct;80(19):9519-29 (2006)