AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence.
Mol. Ther., Oct;20(10):1902-11 (2012)
Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.
Mol. Ther., Oct;20(10):1912-23 (2012)
In vivo selection of transplanted hepatocytes by pharmacological inhibition of fumarylacetoacetate hydrolase in wild-type mice.
Mol. Ther., Oct;20(10):1981-7 (2012)
Aneuploidy as a mechanism for stress-induced liver adaptation.
J. Clin. Invest., Sep;122(9):3307-15 (2012)
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.
Cell Stem Cell., Jul;11(1):36-49 (2012)
AAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivo.
Hum. Gene Ther., Jun;23(6):658-65 (2012)
Frequent aneuploidy among normal human hepatocytes.
Gastroenterology., Jan;142(1):25-8 (2012)
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.
J. Exp. Med., Sep;208(10):1963-76 (2011)
Efficient production of Fah-null heterozygote pigs by chimeric adeno-associated virus-mediated gene knockout and somatic cell nuclear transfer.
Hepatology., Oct;54(4):1351-9 (2011)
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice.
Genes Dev., Jun;25(11):1193-203 (2011)
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential.
Genes Dev., Jun;25(11):1185-92 (2011)
Fanconi anemia-like presentation in an infant with constitutional deletion of 21q including the RUNX1 gene.
Am. J. Med. Genet. A., Jul;155A(7):1673-9 (2011)
Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers.
Mol. Cell. Endocrinol., Jun;339(1-2):144-50 (2011)
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
Cancer Res., Dec;70(23):9959-68 (2010)
The ploidy conveyor of mature hepatocytes as a source of genetic variation.
Nature., Oct;467(7316):707-10 (2010)
Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.
Blood., Dec;116(24):5140-8 (2010)
Chromosomal integration of adenoviral vector DNA in vivo.
J. Virol., Oct;84(19):9987-94 (2010)
Chimeric mice with humanized liver: tools for the study of drug metabolism, excretion, and toxicity.
Methods Mol. Biol., 640:491-509 (2010)
Therapeutic liver reconstitution with murine cells isolated long after death.
Gastroenterology., Sep;139(3):1019-29 (2010)
Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology.
PLoS ONE., 5(2):e9200 (2010)