High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era.
Neuro-oncology., Oct (2012)
Cellular Delivery of Doxorubicin via pH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(Î²-L-Malic Acid).
Int J Mol Sci., 13(9):11681-93 (2012)
Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers.
Biomaterials., Jan;34(1):217-25 (2013)
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases.
Cochrane Database Syst Rev., 9:CD006121 (2012)
Prognosis of patients with multifocal glioblastoma: a case-control study.
J. Neurosurg., Oct;117(4):705-11 (2012)
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma.
Cancer Immunol. Immunother., Jul (2012)
Trends in Surgical Use and Associated Patient Outcomes in the Treatment of Acoustic Neuroma.
World Neurosurg., Jun (2012)
The effect of centralization of caseload for primary brain tumor surgeries: trends from 2001-2007.
Acta Neurochir (Wien)., Aug;154(8):1343-50 (2012)
Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases.
Ann. Surg. Oncol., Aug;19(8):2657-63 (2012)
Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.
PLoS ONE., 7(3):e33684 (2012)
Nanobiopolymer for direct targeting and inhibition of EGFR expression in triple negative breast cancer.
PLoS ONE., 7(2):e31070 (2012)
Alzheimer's disease in the retina: imaging retinal aÎ² plaques for early diagnosis and therapy assessment.
Neurodegener Dis., 10(1-4):285-93 (2012)
Immunotherapy targeting glioma stem cells--insights and perspectives.
Expert Opin Biol Ther., Feb;12(2):165-78 (2012)
Infratentorial supracerebellar resection of a pineal tumor using a high definition video exoscope (VITOMÂ®).
J Clin Neurosci., Feb;19(2):306-9 (2012)
Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease.
Invest. Ophthalmol. Vis. Sci., Nov;52(12):9033-46 (2011)
Vaccines for glioblastoma and high-grade glioma.
Expert Rev Vaccines., Jun;10(6):875-86 (2011)
Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs.
J Drug Deliv., 2011:980720 (2011)
The optimization of polymalic acid peptide copolymers for endosomolytic drug delivery.
Biomaterials., Aug;32(22):5269-78 (2011)
Polymalic acid-based nanobiopolymer provides efficient systemic breast cancer treatment by inhibiting both HER2/neu receptor synthesis and activity.
Cancer Res., Feb;71(4):1454-64 (2011)
Fluorescence lifetime spectroscopy for guided therapy of brain tumors.
Neuroimage., Jan;54 Suppl 1:S125-35 (2011)
Inhibition of brain tumor growth by intravenous poly (Î²-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected].
Proc. Natl. Acad. Sci. U.S.A., Oct;107(42):18143-8 (2010)
Oxidative stimuli-responsive nanoprodrug of camptothecin kills glioblastoma cells.
Bioorg. Med. Chem. Lett., Sep;20(17):5262-8 (2010)
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases.
Cochrane Database Syst Rev., (6):CD006121 (2010)
Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.
Neuroimage., Jan;54 Suppl 1:S204-17 (2011)
T cells enhance stem-like properties and conditional malignancy in gliomas.
PLoS ONE., 5(6):e10974 (2010)
Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy.
J Biomed Opt., 15(2):027008 (2010 Mar-Apr)
Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models.
PLoS ONE., 5(4):e10108 (2010)
Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(Î²-L-malic acid).
Pharm. Res., Nov;27(11):2317-29 (2010)
Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme.
Int. J. Cancer., Nov;127(10):2257-67 (2010)
Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?
Neuroimage., Jan;54 Suppl 1:S106-24 (2011)
Nanoconjugate Platforms Development Based in Poly(Î²,L-Malic Acid) Methyl Esters for Tumor Drug Delivery.
J Nanotechnol., 2010 (2010)
Glioma stem cell research for the development of immunotherapy.
Neurosurg. Clin. N. Am., Jan;21(1):159-66 (2010)
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes.
Brain Res. Bull., Feb;81(2-3):262-72 (2010)
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
J. Neurochem., Dec;111(6):1409-24 (2009)
Chemokine CXC receptor 4--mediated glioma tumor tracking by bone marrow--derived neural progenitor/stem cells.
Mol. Cancer Ther., Sep;8(9):2746-53 (2009)
Isolation of tumour stem-like cells from benign tumours.
Br. J. Cancer., Jul;101(2):303-11 (2009)
Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens.
Stem Cells., Aug;27(8):1734-40 (2009)
High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.
Mol. Cancer Res., May;7(5):665-77 (2009)
DCVax-Brain and DC vaccines in the treatment of GBM.
Expert Opin Investig Drugs., Apr;18(4):509-19 (2009)
Preparation and characterization of antioxidant nanospheres from multiple alpha-lipoic acid-containing compounds.
Bioorg. Med. Chem. Lett., Mar;19(6):1678-81 (2009)
Stimuli-responsive antioxidant nanoprodrugs of NSAIDs.
Int J Pharm., May;372(1-2):112-24 (2009)
Long-term survival in a child with a central nervous system medulloepithelioma.
J Neurosurg Pediatr., Nov;2(5):339-45 (2008)
Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas.
Stem Cells., Dec;26(12):3018-26 (2008)
Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase.
Cancer Res., Sep;68(17):6978-86 (2008)
PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model.
Brain Res., Sep;1230:290-302 (2008)
Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients.
Cancer Res., Jul;68(14):5955-64 (2008)
Different effects of KCa and KATP agonists on brain tumor permeability between syngeneic and allogeneic rat models.
Brain Res., Aug;1227:198-206 (2008)
Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.
Int. J. Cancer., Sep;123(6):1364-75 (2008)
Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.
Clin. Cancer Res., Jun;14(12):4002-9 (2008)
A high-definition exoscope system for neurosurgery and other microsurgical disciplines: preliminary report.
Surg Innov., Mar;15(1):38-46 (2008)
Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery.
Nanomedicine (Lond)., Apr;3(2):247-65 (2008)
Glioblastoma multiforme cells: expression of erythropoietin receptor and response to erythropoietin.
Int. J. Oncol., Nov;31(5):1193-8 (2007)
Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid).
J Control Release., Oct;122(3):356-63 (2007)
Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells.
Stem Cells., Jul;25(7):1645-53 (2007)
Mahaley Clinical Research Award: chemosensitization of glioma through dendritic cell vaccination.
Clin Neurosurg., 53:345-51 (2006)
Nanoconjugate based on polymalic acid for tumor targeting.
Chem. Biol. Interact., Jan;171(2):195-203 (2008)
Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model.
Mol. Cancer., 6:22 (2007)
Malignant astroblastoma with rhabdoid morphology.
J. Neurooncol., Jul;83(3):277-8 (2007)
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo.
Clin. Cancer Res., Feb;13(3):1045-52 (2007)
KLF6: mutational analysis and effect on cancer cell proliferation.
Int. J. Oncol., Jan;30(1):65-72 (2007)
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma.
Mol. Cancer., 5:67 (2006)
Manipulation of proliferation and differentiation of human bone marrow-derived neural stem cells in vitro and in vivo.
J. Neurosci. Res., Feb;85(2):310-20 (2007)
Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis.
Angiogenesis., 9(4):183-91 (2006)
Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells.
Cancer Res., Sep;66(17):8887-96 (2006)
Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides. Case Report.
Neurosurg Focus., 9(6):e8 (2000)
Sensitization of malignant glioma to chemotherapy through dendritic cell vaccination.
Expert Rev Vaccines., Apr;5(2):233-47 (2006)
Polycefin, a new prototype of a multifunctional nanoconjugate based on poly(beta-L-malic acid) for drug delivery.
Bioconjug. Chem., 17(2):317-26 (2006 Mar-Apr)
Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma.
Cancer Res., Mar;66(5):2630-8 (2006)
Diagnosis of meningioma by time-resolved fluorescence spectroscopy.
J Biomed Opt., 10(6):064026 (2005 Nov-Dec)
Improving the delivery of therapeutic agents to CNS neoplasms: a clinical review.
Front. Biosci., 11:1466-78 (2006)
A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells.
J. Biol. Chem., Mar;281(10):6165-74 (2006)
Changes in laminin isoforms associated with brain tumor invasion and angiogenesis.
Front. Biosci., 11:81-8 (2006)
Dendritic cell-based immunotherapy for malignant gliomas.
Expert Rev Neurother., Jul;5(4):497-508 (2005)
Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases.
Breast Cancer Res., 7(4):R411-21 (2005)
T cell immunity in patients with malignant glioma: recent progress in dendritic cell-based immunotherapeutic approaches.
Front. Biosci., 10:2908-21 (2005)
Dendritic cell vaccines and immunity in glioma patients.
Front. Biosci., 10:2861-81 (2005)
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
Oncogene., Aug;24(33):5226-34 (2005)
Dendritic cell vaccines and obstacles to beneficial immunity in glioma patients.
Curr. Opin. Mol. Ther., Feb;7(1):35-47 (2005)
Cellular immunity in the treatment of brain tumors.
Clin Neurosurg., 51:132-9 (2004)
Isolation of cancer stem cells from adult glioblastoma multiforme.
Oncogene., Dec;23(58):9392-400 (2004)
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).
Oncogene., Jan;24(3):344-54 (2005)
Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma.
J. Immunol., Oct;173(7):4352-9 (2004)
Fluorescence lifetime spectroscopy of glioblastoma multiforme.
Photochem. Photobiol., 80:98-103 (2004 Jul-Aug)
Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination.
Clin. Cancer Res., Aug;10(16):5316-26 (2004)
Association between laminin-8 and glial tumor grade, recurrence, and patient survival.
Cancer., Aug;101(3):604-12 (2004)
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.
Cancer Res., Jul;64(14):4980-6 (2004)
Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma.
Cancer Res., Jul;64(14):4973-9 (2004)
Small interference RNA modulation of IL-10 in human monocyte-derived dendritic cells enhances the Th1 response.
Eur. J. Immunol., Jun;34(6):1680-7 (2004)
Recent progress in immunotherapy for malignant glioma: treatment strategies and results from clinical trials.
Cancer Control., 11(3):192-207 (2004 May-Jun)
Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor.
Cancer Control., 11(3):165-73 (2004 May-Jun)
Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4.
Neoplasia., 6(3):287-93 (2004 May-Jun)
AIM-2: a novel tumor antigen is expressed and presented by human glioma cells.
J. Immunother., 27(3):220-6 (2004 May-Jun)
Imprinting status of DLK1 gene in brain tumors and lymphomas.
Int. J. Oncol., Apr;24(4):1011-5 (2004)
Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity.
J. Immunol., Feb;172(3):1602-11 (2004)
Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model.
Cancer Res., Dec;63(24):8899-911 (2003)
Ligands for PPARgamma and RAR cause induction of growth inhibition and apoptosis in human glioblastomas.
J. Neurooncol., Nov;65(2):107-18 (2003)
Use of neural stem cells as therapeutic vehicles for the treatment of malignant glioma.
Expert Rev Neurother., Nov;3(6):883-95 (2003)
Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro.
Mol. Cancer Ther., Oct;2(10):985-94 (2003)
Thymic CD8+ T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality.
J. Immunol., Nov;171(9):4927-33 (2003)