The transcriptional coactivators, PGC-1Î± and Î², cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance.
J. Mol. Cell. Cardiol., Mar;52(3):701-10 (2012)
Peroxisome proliferator activated receptor-alpha (PPARÎ±) and PPAR gamma coactivator-1alpha (PGC-1Î±) regulation of cardiac metabolism in diabetes.
Pediatr Cardiol., Mar;32(3):323-8 (2011)
Mitochondrial dysfunction in diabetic cardiomyopathy.
Biochim. Biophys. Acta., Jul;1813(7):1351-9 (2011)
Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators.
Circulation., Jan;121(3):426-35 (2010)
Symptom occurrence and associated clinical factors in nursing home residents with cancer.
Res Nurs Health., Aug;32(4):453-64 (2009)
Unmet symptom management needs of nursing home residents with cancer.
Cancer Nurs., 31(4):265-73 (2008 Jul-Aug)
Lipotoxicity: what is the fate of fatty acids?
J. Lipid Res., Jul;49(7):1375-6 (2008)
The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium.
PPAR Res., 2008:253817 (2008)
Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.
Circulation., Feb;115(7):909-17 (2007)
Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
Am. J. Physiol. Heart Circ. Physiol., Jan;292(1):H318-25 (2007)
Chronic xanthine oxidase inhibition prevents myofibrillar protein oxidation and preserves cardiac function in a transgenic mouse model of cardiomyopathy.
Am. J. Physiol. Heart Circ. Physiol., Oct;289(4):H1512-8 (2005)