JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR.
Int J Clin Exp Med., 6(1):16-25 (2013)
Emergency Department inter-hospital transfer for post-cardiac arrest care: Initial experience with implementation of a regional cardiac resuscitation center in the United States.
Resuscitation., Sep (2012)
Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association.
Circulation., Sep;126(11):1408-28 (2012)
Therapeutic hypothermia and vasopressor dependency after cardiac arrest.
Resuscitation., Aug (2012)
Bacterial RNA induces myocyte cellular dysfunction through the activation of PKR.
J Thorac Dis., Apr;4(2):114-25 (2012)
Antimicrobial therapeutic determinants of outcomes from septic shock among patients with cirrhosis.
Hepatology., Dec;56(6):2305-2315 (2012)
Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instability.
J Crit Care., Oct;27(5):531.e1-7 (2012)
The role of immunostimulatory nucleic acids in septic shock.
Int J Clin Exp Med., 5(1):1-23 (2012)
Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury.
J Thorac Dis., Feb;4(1):30-9 (2012)
Editor's note: Notice of retraction.
Crit. Care Med., Oct;39(10):2389 (2011)
Septic sera induces apoptosis and DNA fragmentation factor 40 activation in fibroblasts.
Biochem. Biophys. Res. Commun., Aug;412(2):260-5 (2011)
Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest.
Circulation., Jun;123(23):2717-22 (2011)
The pathophysiology of septic shock.
Crit Care Nurs Clin North Am., Mar;23(1):41-66 (2011)
TAKEDA-143242 increased survival via reduced cytokines in porcine peritonitis.
J. Surg. Res., Apr;166(2):e165-73 (2011)
Targeting host E-selectin expression by antisense oligodeoxynucleotides as potential antiendotoxin therapy in vivo.
Oligonucleotides., Oct;20(5):253-61 (2010)
Ventricular dilation is associated with improved cardiovascular performance and survival in sepsis.
Chest., Oct;138(4):848-55 (2010)
Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality.
JAMA., Jun;303(21):2165-71 (2010)
A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitation.
Crit. Care Med., Apr;38(4):1092-100 (2010)
The pathophysiology of septic shock.
Crit Care Clin., Oct;25(4):677-702, vii (2009)
Significance of arterial hypotension after resuscitation from cardiac arrest.
Crit. Care Med., Nov;37(11):2895-903; quiz 2904 (2009)
Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.
Chest., Nov;136(5):1237-48 (2009)
Characterization of human septic sera induced gene expression modulation in human myocytes.
Int J Clin Exp Med., 2(2):131-48 (2009)
Microbiology, time course and clinical characteristics of infection in critically ill patients receiving packed red blood cell transfusion.
Vox Sang., Nov;97(4):294-302 (2009)
Point-of-care assessment of microvascular blood flow in critically ill patients.
Intensive Care Med., Oct;35(10):1761-6 (2009)
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.
Shock., Jul;32(1):35-9 (2009)
Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique.
Resuscitation., Aug;80(8):893-7 (2009)
Outcome measures utilized in clinical trials of interventions for post-cardiac arrest syndrome: a systematic review.
Resuscitation., Jun;80(6):617-23 (2009)
Cardiogenic shock: a historical perspective.
Crit Care Clin., Jan;25(1):103-14, viii (2009)
Sepsis and septic shock: a history.
Crit Care Clin., Jan;25(1):83-101, viii (2009)
Crit Care Clin., Jan;25(1):xiii-xiv (2009)
Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis.
Intensive Care Med., Apr;35(4):748-54 (2009)
Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy.
Intensive Care Med., May;35(5):871-81 (2009)
Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation.
J Crit Care., Dec;23(4):532-6 (2008)
Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality.
Resuscitation., Dec;79(3):410-6 (2008)
Assessment of asymmetric lung disease in intensive care unit patients using vibration response imaging.
Anesth. Analg., Oct;107(4):1243-7 (2008)
Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study.
Acad Emerg Med., Jun;15(6):499-505 (2008)
Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis.
Intensive Care Med., Dec;34(12):2210-7 (2008)
The golden hour of right ventricular ischemia.
Crit. Care Med., Jul;36(7):2194-5 (2008)
Image-based monitoring of one-lung ventilation.
Eur J Anaesthesiol., Dec;25(12):995-1001 (2008)
Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.
Acad Emerg Med., May;15(5):399-413 (2008)
Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock.
Crit Care., 12(2):R35 (2008)
Case report: vibration response imaging findings following inadvertent esophageal intubation.
Can J Anaesth., Mar;55(3):172-6 (2008)
Septic shock--vasopressin, norepinephrine, and urgency.
N. Engl. J. Med., Feb;358(9):954-6 (2008)
Crit. Care Med., Jan;36(1 Suppl):S66-74 (2008)
Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice.
Crit Care., 11(6):R125 (2007)
Dynamic visualization of lung sounds with a vibration response device: a case series.
Respiration., 75(1):60-72 (2008)
Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.
Eur. Heart J., May;28(9):1109-16 (2007)
Serum lactate as a predictor of mortality in patients with infection.
Intensive Care Med., Jun;33(6):970-7 (2007)
Heart Fail Clin., Oct;1(3):419-29 (2005)
Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation mode.
Crit Care., 11(1):R26 (2007)
Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.
Am. J. Physiol. Regul. Integr. Comp. Physiol., May;292(5):R1900-6 (2007)
Transforming growth factor-beta1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum.
Crit. Care Med., Feb;35(2):358-64 (2007)
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival.
Ann Emerg Med., Jan;49(1):88-98, 98.e1-2 (2007)
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Crit. Care Med., Jun;34(6):1589-96 (2006)
Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department.
Chest., Feb;129(2):225-32 (2006)
The future of hospital economic health.
Crit. Care Med., Mar;34(3 Suppl):S88-93 (2006)
Economics of critical care: Medicare part A versus part B payments.
Crit. Care Med., Mar;34(3 Suppl):S82-7 (2006)
Porcine models of severe sepsis: emphasis on porcine peritonitis.
Shock., Dec;24 Suppl 1:75-81 (2005)
The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.
J. Infect. Dis., Jan;193(2):251-8 (2006)
Crit. Care Med., Dec;33(12 Suppl):S482-4 (2005)
Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes.
J. Biol. Chem., Dec;280(52):42619-26 (2005)
Severe sepsis and therapy with activated protein C.
N. Engl. J. Med., Sep;353(13):1398-400 (2005)
Our Journal, Critical Care Medicine, in 2005: high impact factor, rapid manuscript review, growing submissions, and widespread distribution.
Crit. Care Med., May;33(5):923-4 (2005)
Neutralization of endotoxin by a phospholipid emulsion in healthy volunteers.
J. Infect. Dis., May;191(9):1515-22 (2005)
The effect of percutaneous transmyocardial laser revascularization on left ventricular function in a porcine model of hibernating myocardium: a pilot study.
Cardiovasc. Radiat. Med., 5(3):132-5 (2004 Jul-Sep)
Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Crit. Care Med., Feb;33(2):331-40 (2005)
Inclusion criteria for clinical trials in sepsis: did the American College of Chest Physicians/Society of Critical Care Medicine consensus conference definitions of sepsis have an impact?
Chest., Jan;127(1):242-5 (2005)
Vasopressor and inotropic support in septic shock: an evidence-based review.
Crit. Care Med., Nov;32(11 Suppl):S455-65 (2004)
Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531.
Chest., Sep;126(3):860-7 (2004)
Immediate and 1-year survival of out-of-hospital cardiac arrest victims in southern New Jersey: 1995-2000.
Pacing Clin Electrophysiol., Aug;27(8):1072-6 (2004)
Critical care medicine as a distinct product line with substantial financial profitability: the role of business planning.
Crit. Care Med., May;32(5):1207-14 (2004)
Bacterial DNA and RNA induce rat cardiac myocyte contraction depression in vitro.
Shock., Apr;21(4):364-9 (2004)
Preload-independent mechanisms contribute to increased stroke volume following large volume saline infusion in normal volunteers: a prospective interventional study.
Crit Care., Jun;8(3):R128-36 (2004)
Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects.
Crit. Care Med., Mar;32(3):691-9 (2004)
Effect of large volume infusion on left ventricular volumes, performance and contractility parameters in normal volunteers.
Intensive Care Med., Jul;30(7):1361-9 (2004)
Changes in coronary endothelial function predict progression of allograft vasculopathy after heart transplantation.
J. Heart Lung Transplant., Mar;23(3):265-71 (2004)
Abnormal ECG in man admitted to ICU with chest pain and irregular pulse.
Chest., Feb;125(2):775-6 (2004)
Mediator modulation therapy of severe sepsis and septic shock: does it work?
Crit. Care Med., Jan;32(1):282-6 (2004)
Comparison of echocardiography using tissue harmonics and contrast harmonics with radionuclide angiography for the assessment of left ventricular function.
J. Investig. Med., Nov;51(6):366-72 (2003)
Pediatric Critical Care Medicine: Another member of the critical care family.
Pediatr Crit Care Med., Jul;1(1):1 (2000)
Introducing a new editor for Pediatric Critical Care Medicine: Patrick M. Kochanek, MD.
Pediatr Crit Care Med., Apr;2(2):105 (2001)
Cardiac disease in myasthenia gravis: a literature review.
J Clin Neuromuscul Dis., Jun;4(4):199-203 (2003)