Dr. John Carpenter
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Dr. John Carpenter
Dr. John Carpenter
New Windsor, NY
I specialize in
Dentistry - Cosmetic
I have been in practice
My answers and insights have
Helped 50 people
Here are kind words from others
This Thanksgiving, I wanted to share my appreciation for all that you do! Thank you, doctor! :)
Dr. Carpenter is an amazing doctor! #nationaldoctorsday2015 #virtualflower1
I am located at
272 Quassaick Ave
New Windsor , NY 12553
Mon 8:00am - 6:00pm
Tue 8:00am - 7:00pm
Wed 8:00am - 3:00pm
Thu 10:00am - 7:00pm
I was educated and trained at
Medical / Graduate School
Tufts University School of Dental Medicine
Dr. John Carpenter M
I've won the following awards
Diplomate, International Congress of Oral Implantologists
Mastership, Academy of General Dentistrey
Accelerated stability studies of abatacept formulations: comparison of freeze-thawing- and agitation-induced stresses.
J Pharm Sci., Jul;101(7):2307-15 (2012)
Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate.
J Pharm Sci., Jun;101(6):2009-16 (2012)
Selective domain stabilization as a strategy to reduce fusion protein aggregation.
J Pharm Sci., Apr;101(4):1400-9 (2012)
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.
J Pharm Sci., Mar;101(3):946-54 (2012)
Critical evaluation and guidance for using the Coulter method for counting subvisible particles in protein solutions.
J Pharm Sci., Jan;101(1):140-53 (2012)
Glass particles as an adjuvant: a model for adverse immunogenicity of therapeutic proteins.
J Pharm Sci., Nov;100(11):4953-64 (2011)
Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange.
J Pharm Sci., May (2011)
Effects of surfaces and leachables on the stability of biopharmaceuticals.
J Pharm Sci., Apr (2011)
Quaternary conformational stability: The effect of reversible self-association on the fibrillation of two insulin analogs.
Biotechnol. Bioeng., Apr (2011)
Structural and functional modifications of corneal crystallin ALDH3A1 by UVB light.
PLoS ONE., 5(12):e15218 (2010)
Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations.
Anal. Biochem., Mar;410(2):191-9 (2011)
Silicone oil microdroplets and protein aggregates in repackaged bevacizumab and ranibizumab: effects of long-term storage and product mishandling.
Invest. Ophthalmol. Vis. Sci., Feb;52(2):1023-34 (2011)
Aggregation of recombinant human botulinum protein antigen serotype C in varying solution conditions: implications of conformational stability for aggregation kinetics.
J Pharm Sci., Mar;100(3):836-48 (2011)
Preservation of differentiation and clonogenic potential of human hematopoietic stem and progenitor cells during lyophilization and ambient storage.
PLoS ONE., 5(9) (2010)
Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway.
J Pharm Sci., Feb;100(2):492-503 (2011)
Adsorption of monoclonal antibodies to glass microparticles.
J Pharm Sci., Jan;100(1):123-32 (2011)
High-molecular-weight aggregates in repackaged bevacizumab.
Retina (Philadelphia, Pa.)., Jun;30(6):887-92 (2010)
Rescue of cystathionine beta-synthase (CBS) mutants with chemical chaperones: purification and characterization of eight CBS mutant enzymes.
J. Biol. Chem., May;285(21):15866-73 (2010)
Buffer-dependent fragmentation of a humanized full-length monoclonal antibody.
J Pharm Sci., Jul;99(7):2962-74 (2010)
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.
J Pharm Sci., May;99(5):2200-8 (2010)
Physical instability of a therapeutic Fc fusion protein: domain contributions to conformational and colloidal stability.
Biochemistry., Dec;48(49):11724-36 (2009)
Protein adsorption and excipient effects on kinetic stability of silicone oil emulsions.
J Pharm Sci., Apr;99(4):1721-33 (2010)
Inhibition of agitation-induced aggregation of an IgG-antibody by hydroxypropyl-beta-cyclodextrin.
J Pharm Sci., Mar;99(3):1193-206 (2010)
Aggregation of a monoclonal antibody induced by adsorption to stainless steel.
Biotechnol. Bioeng., Jan;105(1):121-9 (2010)
Immunogenicity of aggregates of recombinant human growth hormone in mouse models.
J Pharm Sci., Sep;98(9):3247-64 (2009)
Evidence of partial unfolding of proteins at the ice/freeze-concentrate interface by infrared microscopy.
J Pharm Sci., Sep;98(9):3239-46 (2009)
Monoclonal antibody interactions with micro- and nanoparticles: adsorption, aggregation, and accelerated stress studies.
J Pharm Sci., Sep;98(9):3218-38 (2009)
Understanding and modulating opalescence and viscosity in a monoclonal antibody formulation.
J Pharm Sci., Jan;99(1):82-93 (2010)
Aggregation of human serum albumin during a thermal viral inactivation step.
Int. J. Biol. Macromol., Aug;45(2):91-6 (2009)
Light-induced aggregation of type I soluble tumor necrosis factor receptor.
J Pharm Sci., Sep;98(9):3182-99 (2009)
Response of a concentrated monoclonal antibody formulation to high shear.
Biotechnol. Bioeng., Aug;103(5):936-43 (2009)
Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.
J Pharm Sci., Sep;98(9):3167-81 (2009)
Role of electrostatic repulsion on colloidal stability of Bacillus halmapalus alpha-amylase.
Biochim. Biophys. Acta., Jul;1794(7):1058-65 (2009)
Precipitation of a monoclonal antibody by soluble tungsten.
J Pharm Sci., Sep;98(9):3290-301 (2009)
Evaluation of chemical degradation of a trivalent recombinant protein vaccine against botulinum neurotoxin by LysC peptide mapping and MALDI-TOF mass spectrometry.
J Pharm Sci., Sep;98(9):2994-3012 (2009)
Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality.
J Pharm Sci., Apr;98(4):1201-5 (2009)
Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution.
J Pharm Sci., Sep;98(9):2970-93 (2009)
Mixing properties of lyophilized protein systems: a spectroscopic and calorimetric study.
J Pharm Sci., Sep;98(9):2954-69 (2009)
Preparation of active proteins, vaccines and pharmaceuticals as fine powders using supercritical or near-critical fluids.
Pharm. Res., Sep;25(9):1967-90 (2008)
Influence of protein conformation and adjuvant aggregation on the effectiveness of aluminum hydroxide adjuvant in a model alkaline phosphatase vaccine.
J Pharm Sci., Jan;98(1):114-21 (2009)
IgG particle formation during filling pump operation: a case study of heterogeneous nucleation on stainless steel nanoparticles.
J Pharm Sci., Jan;98(1):94-104 (2009)
Long-term storage of proteins.
Curr Protoc Protein Sci., May;Chapter 4:Unit 4.6 (2002)
Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations.
J Pharm Sci., Dec;97(12):5132-46 (2008)
Influence of particle size and antigen binding on effectiveness of aluminum salt adjuvants in a model lysozyme vaccine.
J Pharm Sci., Dec;97(12):5252-62 (2008)
Measurement of the second osmotic virial coefficient for protein solutions exhibiting monomer-dimer equilibrium.
Anal. Biochem., Jun;377(2):128-33 (2008)
Solid state chemistry of proteins: II. The correlation of storage stability of freeze-dried human growth hormone (hGH) with structure and dynamics in the glassy solid.
J Pharm Sci., Dec;97(12):5106-21 (2008)
Working to improve healthcare for people in developing countries.
J Pharm Sci., Mar;97(3):1039-40 (2008)
High concentration formulations of recombinant human interleukin-1 receptor antagonist: I. Physical characterization.
J Pharm Sci., Aug;97(8):3035-50 (2008)
High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics.
J Pharm Sci., Aug;97(8):3005-21 (2008)
Inhibition of aggregation of aluminum hydroxide adjuvant during freezing and drying.
J Pharm Sci., Jun;97(6):2049-61 (2008)
Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze-thawing.
J Pharm Sci., May;97(5):1801-12 (2008)
Characterization of amorphous solids with weak glass transitions using high ramp rate differential scanning calorimetry.
J Pharm Sci., Feb;97(2):1013-24 (2008)
Effects of solution conditions and surface chemistry on the adsorption of three recombinant botulinum neurotoxin antigens to aluminum salt adjuvants.
J Pharm Sci., Sep;96(9):2375-89 (2007)
Oxidation of methionine residues in recombinant human interleukin-1 receptor antagonist: implications of conformational stability on protein oxidation kinetics.
Biochemistry., May;46(21):6213-24 (2007)
Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1.
J. Biol. Chem., Feb;282(7):4382-92 (2007)
Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity.
J Pharm Sci., Feb;96(2):268-79 (2007)
High-pressure studies on protein aggregates and amyloid fibrils.
Meth. Enzymol., 413:237-53 (2006)
Infrared microscopy for in situ measurement of protein secondary structure during freezing and freeze-drying.
J Pharm Sci., Jan;96(1):179-95 (2007)
Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor.
J Pharm Sci., Jul;95(7):1480-97 (2006)
BSA degradation under acidic conditions: a model for protein instability during release from PLGA delivery systems.
J Pharm Sci., Jul;95(7):1626-39 (2006)
Temperature dependence of benzyl alcohol- and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist.
Biochemistry., Mar;45(12):3898-911 (2006)
Secondary structures of proteins adsorbed onto aluminum hydroxide: infrared spectroscopic analysis of proteins from low solution concentrations.
Anal. Biochem., Apr;351(2):282-9 (2006)
Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure.
Protein Sci., Feb;15(2):304-13 (2006)
Calcium-induced changes to the molecular conformation and aggregate structure of beta-casein at the air-water interface.
Biomacromolecules., 6(6):3334-44 (2005 Nov-Dec)
Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist.
J Pharm Sci., Dec;94(12):2735-48 (2005)
High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: thermodynamics, kinetics, and application to accelerated formulation studies.
Protein Sci., Sep;14(9):2258-66 (2005)
Noninvasive determination of protein conformation in the solid state using near infrared (NIR) spectroscopy.
J Pharm Sci., Sep;94(9):2030-8 (2005)
Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation.
J Pharm Sci., Jun;94(6):1368-81 (2005)
Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations.
J Pharm Sci., Feb;94(2):382-96 (2005)
Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation.
J Pharm Sci., Feb;94(2):256-74 (2005)
Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution.
J Pharm Sci., Dec;93(12):3076-89 (2004)
High-pressure refolding of bikunin: efficacy and thermodynamics.
Protein Sci., Oct;13(10):2639-50 (2004)
Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy.
J Pharm Sci., Oct;93(10):2439-47 (2004)
Cryopreservation of stem cells using trehalose: evaluation of the method using a human hematopoietic cell line.
Stem Cells Dev., Jun;13(3):295-305 (2004)
Infrared spectroscopic studies of protein formulations containing glycine.
J Pharm Sci., May;93(5):1359-66 (2004)
Effects of sucrose on rFVIIa aggregation and methionine oxidation.
Eur J Pharm Sci., Apr;21(5):597-606 (2004)
Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures.
J Pharm Sci., Mar;93(3):684-96 (2004)
Effects of potassium bromide disk formation on the infrared spectra of dried model proteins.
J Pharm Sci., Feb;93(2):496-506 (2004)
Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation.
Pharm. Res., Sep;20(9):1325-36 (2003)
Effects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteins.
Protein Sci., Jun;12(6):1252-61 (2003)
Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.
Protein Sci., May;12(5):903-13 (2003)
Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma.
J Pharm Sci., Apr;92(4):715-29 (2003)
Ultraviolet radiation decreases expression and induces aggregation of corneal ALDH3A1.
Chem. Biol. Interact., Feb;143-144:45-53 (2003)
Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis.
Biochemistry., Jan;42(3):829-37 (2003)
Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation.
J. Biol. Chem., Mar;278(12):10842-50 (2003)
The effect of mutations on the structure of insulin fibrils studied by Fourier transform infrared (FTIR) spectroscopy and electron microscopy.
J Pharm Sci., Dec;91(12):2473-80 (2002)
Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme.
Biochemistry., Sep;41(37):11126-33 (2002)
Effect of glycine on pH changes and protein stability during freeze-thawing in phosphate buffer systems.
J Pharm Sci., Sep;91(9):1969-79 (2002)
Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations.
J Pharm Sci., Jun;91(6):1474-87 (2002)
High-pressure refolding of disulfide-cross-linked lysozyme aggregates: thermodynamics and optimization.
Biotechnol. Prog., 18(3):565-71 (2002 May-Jun)
The Retrofit of an Existing Removable Partial Denture with Implants: A Case Report
Implant Practice US, Vol. 3 Number 2
Management of a Patient Who Developed Uncontrolled Diabetes after Implant Placement: A Case Report
The Journal of Implant and Advanced Clinical Dentistry, Vol. 2, No. 5
Dr. John Carpenter M