Accelerated stability studies of abatacept formulations: comparison of freeze-thawing- and agitation-induced stresses.
J Pharm Sci., Jul;101(7):2307-15 (2012)
Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate.
J Pharm Sci., Jun;101(6):2009-16 (2012)
Selective domain stabilization as a strategy to reduce fusion protein aggregation.
J Pharm Sci., Apr;101(4):1400-9 (2012)
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.
J Pharm Sci., Mar;101(3):946-54 (2012)
Critical evaluation and guidance for using the Coulter method for counting subvisible particles in protein solutions.
J Pharm Sci., Jan;101(1):140-53 (2012)
Glass particles as an adjuvant: a model for adverse immunogenicity of therapeutic proteins.
J Pharm Sci., Nov;100(11):4953-64 (2011)
Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange.
J Pharm Sci., May (2011)
Effects of surfaces and leachables on the stability of biopharmaceuticals.
J Pharm Sci., Apr (2011)
Quaternary conformational stability: The effect of reversible self-association on the fibrillation of two insulin analogs.
Biotechnol. Bioeng., Apr (2011)
Structural and functional modifications of corneal crystallin ALDH3A1 by UVB light.
PLoS ONE., 5(12):e15218 (2010)
Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations.
Anal. Biochem., Mar;410(2):191-9 (2011)
Silicone oil microdroplets and protein aggregates in repackaged bevacizumab and ranibizumab: effects of long-term storage and product mishandling.
Invest. Ophthalmol. Vis. Sci., Feb;52(2):1023-34 (2011)
Aggregation of recombinant human botulinum protein antigen serotype C in varying solution conditions: implications of conformational stability for aggregation kinetics.
J Pharm Sci., Mar;100(3):836-48 (2011)
Preservation of differentiation and clonogenic potential of human hematopoietic stem and progenitor cells during lyophilization and ambient storage.
PLoS ONE., 5(9) (2010)
Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway.
J Pharm Sci., Feb;100(2):492-503 (2011)
Adsorption of monoclonal antibodies to glass microparticles.
J Pharm Sci., Jan;100(1):123-32 (2011)
High-molecular-weight aggregates in repackaged bevacizumab.
Retina (Philadelphia, Pa.)., Jun;30(6):887-92 (2010)
Rescue of cystathionine beta-synthase (CBS) mutants with chemical chaperones: purification and characterization of eight CBS mutant enzymes.
J. Biol. Chem., May;285(21):15866-73 (2010)
Buffer-dependent fragmentation of a humanized full-length monoclonal antibody.
J Pharm Sci., Jul;99(7):2962-74 (2010)
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.
J Pharm Sci., May;99(5):2200-8 (2010)