Dr. Golder Wilson
Dr. Golder Wilson
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Dr. Wilson is an amazing doctor! #nationaldoctorsday2015 #virtualflower1
Dr. Wilson is an amazing doctor! #nationaldoctorsday2015 #virtualflower1
Dr. Golder Wilson
I've won the following awards
HealthTap Founding Doctor
When you must give a baby's parents terrible news.
Med Econ., Feb;73(3):247-8, 251-2, 255 (1996)
Down syndrome: perinatal complications and counseling experiences in 216 patients.
Am. J. Med. Genet., Jun;89(2):96-9 (1999)
Novel assay for Roberts syndrome assigns variable phenotypes to one complementation group.
Am. J. Med. Genet., Jul;93(3):223-9 (2000)
Strand-selective transcription of globin genes in rabbit erythroid cells and chromatin.
Proc. Natl. Acad. Sci. U.S.A., Dec;72(12):4835-9 (1975)
Activation and inactivation of genes determining hemoglobin types.20s.
J. Cell. Physiol., Apr;85(2 Pt 2 Suppl 1):477-94 (1975)
Duplication 8 [inv dup(8)(p12p23)] with macrocephaly.
Ann. Genet., 44(4):195-9 (2001)
Cell-free transcription of mammalian chromatin. Quantitative measurement of newly synthesized globin messenger RNA sequences.
J. Biol. Chem., Nov;250(22):8604-13 (1975)
Coming together for blastogenesis.
Am. J. Med. Genet. A., Mar;117A(3):309 (2003)
Behavioral assessment of children with Down syndrome using the Reiss psychopathology scale.
Am. J. Med. Genet. A., Apr;118A(3):210-6 (2003)
Biochemical abnormality associated with Smith-Lemli-Opitz syndrome in an infant with features of Rutledge multiple congenital anomaly syndrome confirms that the latter is a variant of the former.
Pediatr. Dev. Pathol., 6(3):270-7 (2003)
Mutational risks in females: genomic imprinting and maternal molecules.
Mutat. Res., Dec;296(1-2):157-65 (1992)
Human congenital anomalies: application of new genetic tools and concepts.
Semin. Perinatol., Dec;16(6):385-400 (1992)
Non-specific X linked mental retardation with aphasia exhibiting genetic linkage to chromosomal region Xp11.
J. Med. Genet., Sep;29(9):629-34 (1992)
A model for human situs determination.
Laterality., 1(4):315-29 (1996)
Tales from the neural genome: the lessons of homozygous porphyria.
Arch. Neurol., Nov;61(11):1650-1 (2004)
Clasped-thumb mental retardation (MASA) syndrome: confirmation of linkage to Xq28.
Am. J. Med. Genet., 43(1-2):408-14 (1992)
Molecular cytogenetic characterization of a familial der(1)del(1)(p36.33)dup(1)(p36.33p36.22) with variable phenotype.
Am. J. Med. Genet. A., Dec;139A(2):136-40 (2005)
Partial trisomy 18 with minimal anomalies: lack of correspondence between phenotypic manifestations and triplicated loci along chromosome 18.
Am. J. Med. Genet., Aug;36(4):506-10 (1990)
Genomics of human dysmorphogenesis.
Am. J. Med. Genet., Jan;42(2):187-96 (1992)
A need for pediatric genetics.
Arch Pediatr Adolesc Med., Oct;161(10):1010 (2007)
Gastrointestinal malformation in genetic disorders: a case of partial trisomy 2q with short esophagus and tubular stomach.
Clin Pediatr (Phila)., Sep;30(9):559-62 (1991)
Al-Awadi/Raas-Rothschild/Schinzel (AARRS) phocomelia syndrome: case report and developmental field analysis.
Am. J. Med. Genet. A., Jul;149A(7):1494-8 (2009)
Cornelia de Lange syndrome with ring chromosome 3.
J. Med. Genet., Feb;28(2):143 (1991)
A user's guide to the elements of standard morphologic terminology: Analysis and database.
Am. J. Med. Genet. A., Jul;152A(7):1627-9 (2010)
Balanced translocation 12/13 and situs abnormalities: homology of early pattern formation in man and lower organisms?
Am. J. Med. Genet., Mar;38(4):601-7 (1991)
Genetic drift. Saving Grace: On the nature of syndromes and the missed Nobel.
Am. J. Med. Genet. A., Mar;155A(3):466-8 (2011)
Interstitial deletion 5q14.3q21.3 with MEF2C haploinsufficiency and mild phenotype: when more is less.
Am. J. Med. Genet. A., Jun;155A(6):1437-41 (2011)
Karyotype/phenotype controversy: genetic and molecular implications of alternative hypotheses.
Am. J. Med. Genet., Aug;36(4):500-5 (1990)
Malformations and minor anomalies in children whose mothers had prenatal diagnosis: comparison between CVS and amniocentesis.
Am. J. Med. Genet., Nov;37(3):366-70 (1990)
Euchromatic 16p+ heteromorphism: first report in North America.
Am. J. Med. Genet., Dec;37(4):548-50 (1990)
Maternal genetic effect in DNA analysis: egg on your traits.
Am. J. Med. Genet. A., Jul;158A(7):1589-93 (2012)
Maternal meiosis II nondisjunction in a case of 47,XXY testicular feminization.
Hum. Genet., Feb;84(3):289-92 (1990)
The frequency of aneuploidy in cultured lymphocytes is correlated with age and gender but not with reproductive history.
Am. J. Hum. Genet., Jun;46(6):1101-11 (1990)
Office approach to the genetics patient.
Pediatr Ann., Feb;19(2):79-91 (1990)
Peroxisomal disorders: clinical commentary and future prospects.
Am. J. Med. Genet., Jul;30(3):771-92 (1988)
Glutaric aciduria type II: review of the phenotype and report of an unusual glomerulopathy.
Am. J. Med. Genet., Mar;32(3):395-401 (1989)
Cell-specific ribosomal DNA spacer variability in human urothelial carcinoma cultures.
J. Urol., Feb;137(2):324-6 (1987)
Effect of aneuploidy and neoplasia on human ribosomal DNA inheritance.
Am J Med Genet Suppl., 3:121-32 (1987)
Obesity and abnormal behaviour associated with interstitial deletion of chromosome 18 (q12.2q21.1).
J. Med. Genet., Jan;26(1):62-3 (1989)
MCA/MR syndrome in a female infant with tetraploidy mosaicism: review of the human polyploid phenotype.
Am. J. Med. Genet., Aug;30(4):953-61 (1988)
Chondrodysplasia punctatas and the peroxisomopathies: overlapping syndrome communities.
Pathol Immunopathol Res., 7(1-2):113-8 (1988)
Occurrence of holoprosencephaly in chromosome 13 disorders cannot be explained by duplication/deficiency of a single locus.
Am J Med Genet Suppl., 2:65-72 (1986)
Heterochrony and human malformation.
Am. J. Med. Genet., Feb;29(2):311-21 (1988)
Further delineation of the G syndrome: a manageable genetic cause of infantile dysphagia.
J. Med. Genet., Mar;25(3):157-63 (1988)
Transcription of chromatin with prokaryotic and eukaryotic polymerases.
Methods Cell Biol., 19:339-57 (1978)
Case study: congenital hypertrophic pyloric stenosis in twins.
Midwives Chron., Mar;100(1190):66-9 (1987)
Molecular analysis of cloned human 18S ribosomal DNA segments.
Proc. Natl. Acad. Sci. U.S.A., Nov;75(11):5367-71 (1978)
Improved growth of human urothelial carcinoma cell cultures.
J. Urol., Oct;136(4):953-9 (1986)
The phenotypic and cytogenetic spectrum of partial trisomy 9.
Am. J. Med. Genet., Feb;20(2):277-82 (1985)
Altered developmental sequences in diabetic embryopathy.
N. Engl. J. Med., Jun;312(23):1519-20 (1985)
Evidence that the human Y chromosome does not contain clustered DNA sequences (BKM) associated with heterogametic sex determination in other vertebrates.
N. Engl. J. Med., Jul;313(4):242-5 (1985)
Phenotypic delineation of ring chromosome 15 and Russell-Silver syndromes.
J. Med. Genet., Jun;22(3):233-6 (1985)
Further delineation of the dup(3q) syndrome.
Am. J. Med. Genet., Sep;22(1):117-23 (1985)
Cell-free transcription of mammalian chromatin: transcription of globin messenger RNA sequences from bone-marrow chromatin with mammalian RNA polymerase.
Proc. Natl. Acad. Sci. U.S.A., Apr;71(4):1219-23 (1974)
Importance of full size complementary DNA in nucleic acid hybridization.
J. Biol. Chem., Jun;251(11):3425-31 (1976)
HeLa cell identification by analysis of ribosomal DNA segment patterns generated by endonuclease restriction.
Am. J. Hum. Genet., Nov;32(6):890-7 (1980)
Structure and variation of human ribosomal DNA: the external transcribed spacer and adjacent regions.
Am. J. Hum. Genet., Jan;34(1):32-49 (1982)
Structure and variation of human ribosomal DNA: molecular analysis of cloned fragments.
Gene., Dec;16(1-3):1-9 (1981)
Individual and evolutionary variation of primate ribosomal DNA transcription initiation regions.
Mol. Biol. Evol., Apr;1(3):221-37 (1984)
Trisomy 9 mosaicism: another etiology for the manifestations of Goldenhar syndrome.
J. Craniofac. Genet. Dev. Biol., 3(4):313-6 (1983)
Cat eye syndrome owing to tetrasomy 22pter leads to q11.
J. Med. Genet., Feb;21(1):60-3 (1984)
Partial trisomy 2q.
Clin. Genet., Mar;23(3):191-4 (1983)
The association of chromosome 3 duplication and the Cornelia de Lange syndrome.
J. Pediatr., Nov;93(5):783-8 (1978)
Recurrence risks of malformations.
J Reprod Med., Sep;27(9):607-12 (1982)
The phenotype of ring chromosome 3.
J. Med. Genet., Dec;19(6):471-3 (1982)
Differential evolution and expression of murine peroxisomal membrane protein genes.
Biochem. Mol. Med., Jun;55(1):22-30 (1995)
Interstitial deletions 4q21.1q25 and 4q25q27: phenotypic variability and relation to Rieger anomaly.
Am. J. Med. Genet., Jan;55(2):165-70 (1995)
Atypical inheritance: new horizons for neurology.
Neurol Clin., Nov;12(4):663-81 (1994)
Structure and expression of mammalian peroxisome assembly factor-1 (PMP35) genes.
Biochem. Med. Metab. Biol., Apr;51(2):140-8 (1994)
Multiple coagulation defects and the Cohen syndrome.
Clin. Genet., Apr;45(4):212-6 (1994)
Genomic imprinting: summary of an NICHD conference.
Am. J. Med. Genet., Jul;46(6):675-80 (1993)
Karyotype/phenotype correlation: prospects and problems illustrated by trisomy 18.
Prog. Clin. Biol. Res., 384:157-73 (1993)
Three cases of dup(10p)/del(10q) syndrome resulting from maternal pericentric inversion.
Am. J. Med. Genet., Nov;47(6):817-9 (1993)
Index finger hyperphalangy and multiple anomalies: Catel-Manzke syndrome?
Am. J. Med. Genet., Apr;46(2):176-9 (1993)
Robertsonian (15q;15q) translocation in a child with Angelman syndrome: evidence of uniparental disomy.
Am. J. Med. Genet., Dec;66(4):426-8 (1996)
Correlated heart/limb anomalies in Mendelian syndromes provide evidence for a cardiomelic developmental field.
Am. J. Med. Genet., Apr;76(4):297-305 (1998)
Thirteen cases of Niikawa-Kuroki syndrome: report and review with emphasis on medical complications and preventive management.
Am. J. Med. Genet., Sep;79(2):112-20 (1998)
Here are some of my top insights
Dr. Golder Wilson
What type of inheritance is involved in spina bifida? In brief: MultifactorialSPINA BIFIDASee 1 more answer
Isolated spina bifida (myelomeningocele) is a neural tube defect along with anencephaly that exhibits multifactorial determination--a combination of many genes and in utero environmental factors that cross a threshold to produce the defect.
If I have a arnold chiari malformation, what are the chances that my son will have these problems too? In brief: LowCHIARI MALFORMATION CHILDREN'S HEALTH ARNOLD-CHIARI SONSee 1 more answer
Chiari malformation can be isolated, occur secondary to spina bifida, or be part of many different patterns of birth defects (syndromes).
Is there neonatal testing for prader-willi syndrome? In brief: YesPRADER-WILLI SYNDROME NEONATALSee 1 more answer
The test for prader-willi is from blood, doing chromosomes with fish for the specific deletion of 15 (60-70% of cases) or looking at dna methylation that shows altered imprinting of the prader-willi/angelman region on chromosome 15 (~30% of cases).
When do you begin to test for tay-sach's? In brief: In infancy
Tay sachs is a degenerative disorder that presents with an exaggerated startle response (~6 months) and has a "cherry red spot" in the retina.
Can I go to a genetic counselor to see if I have familial hypercholesterolemia? In brief: Physician is betterHYPERCHOLESTEROLEMIA COUNSELORS HIGH CHOLESTEROL FAMILIAL HYPERCHOLESTEROLEMIASee 1 more answer
Genetic counselors are master's trained individuals trained to collect and interpret family histories but with little clinical experience.
What is the genetic reason for causing kleinfelter's? In brief: Extra X in menHEIGHT INFERTILITY TALL STATURE KLINEFELTER'S SYNDROMESee 1 more answer
Klinefelter syndrome is usually caused by an extra x chromosome in males, changing their normal 46, xy chromosome constitution to 47, xxy.
Does inbreeding in families cause hemophilia to develop? In brief: Not usuallyHEMOPHILIA CF (CYSTIC FIBROSIS)
Despite emphasis on hemophilia and royal families, rasputin's influence depended on common relatives among english/russian royalty.
How accurate are genetic pedigrees? In brief: Often incomplete
A pedigree is a standard diagram of your family history, using squares for males, circles for females, joining lines for marriage and offspring.
I have a family history of colorectal cancer. When should I begin testing and how often? In brief: Depends on familyCANCER COLORECTAL CANCER PROCTOLOGYSee 1 more answer
You should see a clinical geneticist to document your family history of colon cancer and look for associated symptoms (e.