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Doctor insights on: Immunotherapy

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Dr. Michael Palumbo
1,134 doctors shared insights

Immunotherapy (Overview)

Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or economic value (vs medication)


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Does immunotherapy involve antitoxins?

Does immunotherapy involve antitoxins?

Definition: Immunotherapy indicates the use of immunological mechanisms for treatment. Allergy immunotherapy (allergy shots) do not include antitoxins. Antitoxins are antibodies against toxins and are used whaen toxins are suspected, for example posionous snake bites. This treatment can be called immunotherapy. ...Read more

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Dr. Michael Palumbo
1,134 doctors shared insights

Immunotherapy (Overview)

Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or economic value (vs medication)


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How effective are allergy shots, immunotherapy injections or drops?

Depends: The efficacy of allergy shots (immunotherapy) can be maximized by seeing a board certified allergist. Allergists receive extensive training in treating with allergy shots. In the right patient, they can be curative, and hopefully decrease or eliminate the need for allergy medications. Allergy drops have also been shown to be very effective, but are not yet fda approved. ...Read more

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Is immunotherapy in asthma effective?

Is immunotherapy in asthma effective?

Yes: It is if this is the cause of your asthma. I'm a pulmonologist who regularly refers to allergists for this reason and have had the therapy myself. It works for many sufferers to reduce their symptoms (and sometimes eliminate them). ...Read more

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What is targeted immunotherapy?

Boosting immunity: to fight cancer, that's it in a nutshell, check the following link for more info, http://www.cancer.net/new-targeted-immunotherapy-promising-treatment-several-advanced-cancers ...Read more

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What is venom immunotherapy?

Bee or Wasp allergy: Venom includes bees wasps hornets and fire ants. Immunotherapy is a series of desensitization injections. Most often starting weekly and progressing to every 6 weeks in most cases. There are rush immunotherapy programs in place as well. Traditional immunotherapy continues for 5 years in most cases. ...Read more

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Can montelukast become an alternative of allergens immunotherapy for perenial allergic rhinitis ?

Can montelukast become an alternative of allergens immunotherapy for perenial allergic rhinitis ?

Not really: I suggest 3 steps to controlling allergies : 1) avoid the things you are allergic to. 2) take medications to control the symptoms. 3) get 'allergy shots' (immunotherapy) to teach your body to not be "allergic" to those things (immune tolerance). Using a leukotriene antagonist control the symptoms some, but it is not the most effective medication, and is not an equal alternative to immunotherapy. ...Read more

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Is allergy shots considered immunosuppressive?

Is allergy shots considered immunosuppressive?

Immune regulation: Allergy shots have been around for just over 100 years and have proven to be effective for most people who are allergic. They work through improved regulation of your immune system to reduce to allergic aspect. The most important thing is that many people continue to do well without the shots after having received them for 4-5 years. ...Read more

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Can children receive immunotherapy?

Can children receive immunotherapy?

Yes : Most allergists prefer to start immunotherapy injections around age 5 . Often given to younger patients in hopes of preventing development of asthma in these young patients with nasal allergies. ...Read more

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How effective are monoclonal IgE blockers in allergic rhinitis?

How effective are monoclonal IgE blockers in allergic rhinitis?

IgE antibodies : Theoretically, one would expect monoclonal IgE antibodies to be very effective in blocking the allergic response. In the US, this has not been rigorously tested to establish its effectiveness. It is not FDA approved therapy at this time. However, it is approved for IgE mediated asthmatic disease and can concomitantly help allergic rhinitis in those patients. ...Read more

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How effective are allergy shots for bees allergies?

How effective are allergy shots for bees allergies?

Very effective: After a true bee/wasp/hornet allergy is determined, there is approximately a 40-60% chance of another systemic reaction occurring if stung again without ever receiving allergy shots. However, if a patient receives allergy shots to the specific allergic venom, the risk of another systemic reaction reduces to less than 3%. Consultation with a board-certified allergist is recommended. ...Read more

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How is radio-immunotherapy administered?

How is radio-immunotherapy administered?

In steps: Radio-immunotherapy (rit) is given in three steps, all through an iv. Step 1: an antibody to b cells alone to clear out some normal b cells. Step 2: an antibody to b cells with a small amount of radiation attached, followed by imaging. Step 3: a "hot" antibody to b cells with a larger dose of radiation attached. This acts like a smart bomb to kill cancerous b cells (lymphoma cells). ...Read more

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Where do they inject the needle for allergen immunotherapy (pet allergies)?

Where do they inject the needle for allergen immunotherapy (pet allergies)?

Upper arm: The injection is typically in the back of the upper arm. There are rare circumstances where it varies. However the arm is by far the most common location. ...Read more

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How effective is targeted immunotherapy for treating cancer?

How effective is targeted immunotherapy for treating cancer?

It has generated exc: Immunotherapy is a new area of treatments for Cancer, different than the Targeted therapies of the last 15 years. It has excellent anticancer activity(in Lung Cancer+ more) It works on the human immune system, thus it is not targeted at the Cancer cells but at the immune cells called Lymphocytes which have the ability to kill cancer cells when properly stimulated with the modern immunotherapy drug ...Read more

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Is it possible to get allergy desensitization / immunotherapy shots for food allergies?

Is it possible to get allergy desensitization / immunotherapy shots for food allergies?

No: There are no injection protocols for desensitization to foods. Oral desensitization is being carried out at several research centers, but is not ready for general clinical use at this time. ...Read more

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How effective are Filgrastim (filgrastin) injections for treating leukemia?

How effective are Filgrastim (filgrastin) injections for treating leukemia?

Filgrastim (filgrastin): "Filgrastim is used to decrease the chance of infection in people who have certain types of cancer and are receiving chemotherapy medications that may decrease the number of neutrophils (a type of blood cell needed to fight infection), in people who are undergoing bone marrow transplants, and in people who have severe chronic neutropenia (condition in which there are a low number of neutrophils > ...Read more

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What is Antigen-specific immunotherapy?

What is Antigen-specific immunotherapy?

Specific allergens: If you are referring to allergy treatment, then this simply means that you are given extracts containing the specific allergens you are sensitized to. On the other hand, allergic people are usually less likely to have autoimmune diseases like rheumatoid arthritis which you appear to suffer. Thus you will need to tell us what disease condition this treatment is intended for. ...Read more

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Does immunotherapy work for a shellfish allergy?

Does immunotherapy work for a shellfish allergy?

NO: I am not awwre of any imunothreapy for shellfish allergy.I recomend consulting an allergist to see what options there are ...Read more

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How effective is immunotherapy for treating leukemia?

Still uncertain: At present Immunotherapy is showing much benefit in solid tumors which are lading the way in clinical trials. Such trials are just beginning in Leukemia, so there is no clear data one way or the other/. But it has the potential to be useful like it has already in treating solid cancers like Lung Cancer, Kidney cancer and melanoma. ...Read more

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Are allergy shots more effective as allergy pill treatments?

Are allergy shots more effective as allergy pill treatments?

Yes: They work better, work systemically, give long term symptom control, and reduce the risk of asthma and further sensitizations. ...Read more

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How effective is immunotherapy for treating lymphoma?

How effective is immunotherapy for treating lymphoma?

Very: Original treatment for lymphoma other than localized RT was chemo in combination therapy i.e. CHOPP. Improvement not furthered until the anti-CD 20 drugs became available . Most common was RITUXAN (rituximab) which induces ADCC by attacking CD20 found on both normal and malignant lymphocytes. Stability of WBC since CD 20 antigen not present on the precursor lymphocytes which regenerate q24hrs. ...Read more