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Doctor insights on: Transfusion Related Acute Lung Injury In Children

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Are there any known ways to treat transfusion related acute lung injury?

Are there any known ways to treat transfusion related acute lung injury?

Supportive care: The good news is that trali is treatable. Prevent more damage by reducing the tidal volume on a ventilator and gradually reduce oxygen to minimum. Reduce amount of water. Keep the lungs dry. The lungs will recover with rest. There is no specific medicines. ...Read more

Lung (Definition)

Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more


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What exactly is transfuion related acute lung injury (trali)?

What exactly is transfuion related acute lung injury (trali)?

It can be really bad: It's thought to be immune mediated. It usually occurs within 6 hours of receiving a blood product (red cells, platelets, cryoprecipitate, or plasma) and has a mortality rate approaching 10% in some studies. It causes significant pulmonary edema usually requiring intubation. It usually resolves in 2-4 days with just supportive care alone. ...Read more

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What is transfuion rlated acute lung injury (trali)?

What is transfuion rlated acute lung injury (trali)?

Rare transfusion rxn: Trali is a rare reaction to transfused plasma or platelets. It happens when the donor has formed antibodies to white blood cells. When the transfusion is given, the antibodies attack cells in the person receiving it, causing microscopic injury to the lungs. The can result in breathing difficulties and the need for a ventilator for a period of time. ...Read more

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Can I fly back home while recovering from lung injury?

Can I fly back home while recovering from lung injury?

Depending on surgery: Recent lung resection for cancer vs none cancerous disease vs treatment for recurrent pneumothorax. Just call your surgeon and discuss with him/her about your travel plan. ...Read more

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Could you explain the difference between active lung disease & lung injury?

Could you explain the difference between active lung disease & lung injury?

Ongoing damage: Active lung disease refers to a process that is not under control and can lead to ongoing damage or injury to the lung. Lung injury when acute is a one time event, but when chronic is likely caused by that active lung disease. ...Read more

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How long does a pulmonary edema caused by lung injury take to develop ?

How long does a pulmonary edema caused by lung injury take to develop

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Lung injury edema: depends on the nature and severity of injury but if it's going to occur normally would be apparent within a few days. ...Read more

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What is the difference between active lung disease. Lung injury?

What is the difference between active lung disease. Lung injury?

Cause and Effect: Lung disease can be caused by many factors like cigarette smoking, tuberculosis, lung cancer, asthma, and others. Lung injury could occur from lung disease, trauma to the chest wall/lungs, or inhalation of toxic substance.
So, a lung injury can happen from an isolated sudden accident or it could happen as a result of a disease process. I hope this helps. ...Read more

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What are the difference between lung injury and active lung disease?

What are the difference between lung injury and active lung disease?

Same result: The end result of some interstitial lung disease is the same even though the causes are different. ...Read more

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How do active lung disease&lung injury differ?

How do active lung disease&lung injury differ?

Continuum: An active process can be limited or ongoing-chronic. It can be inflammation, tumor, or trauma or combined.

An injury can be trauma and acute, or chronic like smoking.
Stab wound is acute and an injury.
These words are adjectives describing the situation.
Active- something happening.
Injury a problem, damage etc.
. ...Read more

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Can a old punctured lung injury cause chest pain later in life?

Can a old punctured lung injury cause chest pain later in life?

Not usually: If you have new persistent onset of chest pain esp on left side, it is crucial that you inform your doctor soon to grt a throughout evaluation. ...Read more

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My lung x-rays looked normal, does that mean I have no lung damage ?

My lung x-rays looked normal, does that mean I have no lung damage ?

No: Damage from what? Ct is much more sensitive than is a standard x-ray to look for damage caused by a wide variety of causes. ...Read more

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How can I determine whether I have lung damage from silicate inhalation?

See your doctor: The most effective test would be pulmonary function studies, which will show how your lungs are functioning now. If you had a previous set done, comparison would show what the effects of exposure are. ...Read more

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Is 96 to 98% oxygen levels good I've stopped smoking 10 weeks now is this ok or signs of lung damage and COPD ?

Is 96 to 98% oxygen levels good I've stopped smoking 10 weeks now is this ok or signs of lung damage and COPD ?

Normal.: Anything around 95% or above is normal. 92% can be acceptable for certain disease states, such as copd. To evaluate your lung you'll need to undergo a pulmonary function test (pft), which will help the physician determine if your lungs are functioning within an acceptable range. Discuss with your pcp. ...Read more

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On pulseoxeter my oxygen level is between 95-98 I have stopped smoking have COPD new diagnosed are these levels good even though I've lung damage ?

Ok: Great that you stopped smoking.
Encourage others to avoid smoking and copd.
You will be ok at 95 on room air but likely short of breath with exercize.
Over time you may stabilize or improve a bit. ...Read more

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Please answer! what damages can weed smoking cause you other than lung damage.?

Many: Possible effects of marijuana: anxiety, depression, fear, panic , delusions, paranoia, hallucinations, losing touch with reality, inattentiveness, short-term memory problems, disturbances of thought processes. Fatigue, poor concentration, slowed reaction times ; slowed problem solving. Some people develop a dry mouth, have a rapid heart rate, develop respiratory irritation or may feel hungry. ...Read more

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I was wondering about lung damage brought on by smoking, 10 a day, started at 17, quit at 21. I vigorously exercise now, will lungs completely heal?

I was wondering about lung damage brought on by smoking, 10 a day, started at 17, quit at 21. I vigorously exercise now, will lungs completely heal?

Probably: Any damage done by smoking 10 cigs a day for 4 years is likely to heal completely over time. Congratulations on stopping!
see http://whyquit.Com/whyquit/a_benefits_time_table.Html
for a timetable of how your body heals. ...Read more

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Is there alternative medicine to repair lung damage from smoking?

Is there alternative medicine to repair lung damage from smoking?

Unlikely: Cigarette smoking can cause lung damage from day 1. Stopping today, however, can help to reverse damage caused by smoking; and after 6 months of no smoking, studies have shown that your heart-attack risk can revert to that of a non-smoker! ...Read more

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Can drinking black tea help prevent lung damage?

QUESTIONABLE: I wouldn't bank on it. The following article : http://www.Themedguru.Com/20130326/feature/black-tea-good-diabetes-86147778.Html states “ black tea has a special property to block dna damage associated with tobacco and other toxic chemicals.” red tea & white tea have more health benefits than black tea. If you want healthy lungs then you need to take care of your lungs. Don't smoke. Do exercise. ...Read more

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Is the lung damage from meconium aspiration permanent?

No: Meconium aspiration, per se, is uncommon, and many cases of so-called meconium aspiration are simply other forms of respiratory distress noted in newborns who also passed meconium prior to delivery. True meconium aspiration does cause acute lung injury but most, if not all, cases heal completely within days to weeks. ...Read more

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Do people with lung damage from asthma/repeated bronchitis ever need lung transplants? If so, are they cured of asthma? How bad can lung damage get?

Rarely: Only patients with severe lung damage will need lung transplantation. Lot can be done for COPD using medicines, exercise and not smoking. ...Read more

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I took my pro air hfa inhaler before my pulmonary function testing. Would this affect my results if I have COPD , lung damage, or other diseases ?

I took my pro air hfa inhaler before my pulmonary function testing. Would this affect my results if I have COPD , lung damage, or other diseases ?

It would...: improve reversible airway obstruction, as in asthma. Chronic obstructive lung disease, e.g. emphysema, chronic bronchotis, fibrosis, othet, has much more of a permament, irreversible, and less reversible, component to the obstruction. Drugs like proair have less
of an effect. Lack of a response is one factor in making the diagnosis. ...Read more

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Is lung damage during breast radiation permanent?

Is lung damage during breast radiation permanent?

Generally yes: Acute radiation pneumonitis/lung inflamation can be treated and improve. However, radiation causes longterm injury and progressive fibrosis. This process continues long after the radiation treatment is completed. ...Read more

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Chances of lung damage from breast cancer radiation?

Chances of lung damage from breast cancer radiation?

Low, but depends: The overall risk of lung damage resulting in breathing problems is less than 1-2%, but depends on the size of the radiation field, whether nodes are being treated, the technique (2d, 3d, or imrt), use of chemo during radiation (unusual), and issues with the patient (history of interstitial lung disease , etc). Ask your doctor what techniques they will use to reduce the amount of lung treated. ...Read more

Dr. James Krick
1 doctor shared a insight

Injuries (Definition)

An injury, of any severity, is a condition in which a person has damage to any part of his body. Examples of major injuries include gunshot wounds, knife wounds, large burns, severed ...Read more


Dr. Juan Merayo-Rodriguez
321 doctors shared insights

Transfusions (Definition)

Sometimes babies are given whole blood to supply what they are lacking, and sometimes only components of blood, such as platelets or ...Read more