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Doctor insights on: Thrombolytic Therapy Reperfusion Injury Related

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Are thrombolytic therapy and reperfusion injury related, and how?

Are thrombolytic therapy and reperfusion injury related, and how?

Sort of: Thrombolytic therapy entails breaking off a blocked vessel due to a clot. In the process reperfusion injury can occur to surrounding tissues due to transient lack of oxygen and inflammatory reactions. ...Read more

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Dr. Lynne Weixel
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Injuries (Definition)

An injury, of any severity, is a condition in which a person has damage to any part of his body. Examples of major injuries include gunshot wounds, knife wounds, large burns, severed ...Read more


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Which patients will benefit most from early thrombolytic therapy with intracoron?

Which patients will benefit most from early thrombolytic therapy with intracoron?

Quickness: It all depends on the speed. If the patient can't get to the specialized hospital dealing with angioplasty, he can get some reperfusion quickly in a hospital close-by. ...Read more

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What will happen during thrombolytic therapy?

What will happen during thrombolytic therapy?

Disolve a blood clot: An ischemic stroke is caused by a blood clot blocking a major artery in the brain. The effect of t-pa is to dissolve clots so that blood flow can be restored and viable brain tissue may be saved. T-pa, when introduced into the systemic circulation, binds to the fibrin protein threads of a thrombus and converts the enmeshed plasminogen to plasmin, initiating local fibrinolysis. ...Read more

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Are there side effects for thrombolytic therapy?

Are there side effects for thrombolytic therapy?

Bleeding: There are risks associated with tpa (alteplase). Complications include bleeding into the brain, other types of serious bleeding (e.g., gastrointestinal), and death. It is important to weigh the possibility of benefit against the possibility of harm. In most cases tpa (alteplase) is safe and makes a positive impact on the outcome in stroke patients. ...Read more

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What should be the role of thrombolytic therapy in stroke?

What should be the role of thrombolytic therapy in stroke?

Depends: The role of thrombolytic therapy in stroke is patient specific and should be rendered only at centers accredited for comprehensive stroke care. ...Read more

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Will thrombolytic therapy reduce the size of veins?

Will thrombolytic therapy reduce the size of veins?

Probably: Thrombosis of veins results in an inflammatory response (phlebitis), and this will result in alteration of the vein wall with remodeling and this can result in shrinkage or dilation of the wall. The remaining thrombus present will result in web-like scarring within the vein narrowing the lumen and reducing the diameter. ...Read more

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Why thrombolytic therapy is contraindicated in aortic dissection?

Why thrombolytic therapy is contraindicated in aortic dissection?

Bleeding risk: Because doctors tries to balance the possible benefits to the risk of harm. And here with aortic dissection, there is an increased risk of bleeding that exceed the desired benefit, which makes thrombolytic contraindicated in those patients. ...Read more

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What is thrombolytic therapy?

What is thrombolytic therapy?

Stroke and MI: Thrombolytic therapy is the urgent application of drugs/enzymes that break down blood clots, mainly in arteries to slow down or stop the progression of heart attacks and strokes. Blocked dialysis shunts are also sometimes treated with such medications. Since busting the clot allows blood to flow freely downstream, damage to vital tissue is reduced or sometimes totally halted. ...Read more

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What is thrombolytic therapy?

What  is thrombolytic therapy?

"Clot buster": These are medications that can be given to patients so as to break up blood clots in the lungs, heart, or for strokes and leg clots. These are utilised in situations where improving blood flow to the affected organs is critical. Examples include tpa, (alteplase) streptokinase, etc. ...Read more

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What does thrombolytic therapy involve?

Clot dissolving: Thrombolytic therapy is intended to assist the body's natural mechanism to help dissolve blood clots. These clots can be found in either arteries or veins depending on the underlying problem. I hope this helps! ...Read more

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Dr. Brian Santin
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Clot Buster (Definition)

Clot busters are a kind of ...Read more